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Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss.
He S, Zimmerman MW, Layden HM, Berezovskaya A, Etchin J, Martel MW, Thurston G, Jing CB, van Rooijen E, Kaufman CK, Rodig SJ, Zon LI, Patton EE, Mansour MR, Look AT. He S, et al. Among authors: zimmerman mw. Oncogene. 2021 Sep;40(38):5718-5729. doi: 10.1038/s41388-021-01926-y. Epub 2021 Jul 30. Oncogene. 2021. PMID: 34331013 Free PMC article.
LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis.
Zhu S, Zhang X, Weichert-Leahey N, Dong Z, Zhang C, Lopez G, Tao T, He S, Wood AC, Oldridge D, Ung CY, van Ree JH, Khan A, Salazar BM, Lummertz da Rocha E, Zimmerman MW, Guo F, Cao H, Hou X, Weroha SJ, Perez-Atayde AR, Neuberg DS, Meves A, McNiven MA, van Deursen JM, Li H, Maris JM, Look AT. Zhu S, et al. Among authors: zimmerman mw. Cancer Cell. 2017 Sep 11;32(3):310-323.e5. doi: 10.1016/j.ccell.2017.08.002. Epub 2017 Aug 31. Cancer Cell. 2017. PMID: 28867147 Free PMC article.
MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification.
Zimmerman MW, Liu Y, He S, Durbin AD, Abraham BJ, Easton J, Shao Y, Xu B, Zhu S, Zhang X, Li Z, Weichert-Leahey N, Young RA, Zhang J, Look AT. Zimmerman MW, et al. Cancer Discov. 2018 Mar;8(3):320-335. doi: 10.1158/2159-8290.CD-17-0993. Epub 2017 Dec 28. Cancer Discov. 2018. PMID: 29284669 Free PMC article.
JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.
Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, Pike-Overzet K, Anders L, Berezovskaya A, Zhou Y, Zon LI, Neuberg D, Fielding AK, Staal FJT, Langenau DM, Sanda T, Young RA, Look AT. Mansour MR, et al. Among authors: zimmerman mw. J Exp Med. 2018 Jul 2;215(7):1929-1945. doi: 10.1084/jem.20170484. Epub 2018 Jun 25. J Exp Med. 2018. PMID: 29941549 Free PMC article.
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry.
Durbin AD, Zimmerman MW, Dharia NV, Abraham BJ, Iniguez AB, Weichert-Leahey N, He S, Krill-Burger JM, Root DE, Vazquez F, Tsherniak A, Hahn WC, Golub TR, Young RA, Look AT, Stegmaier K. Durbin AD, et al. Among authors: zimmerman mw. Nat Genet. 2018 Sep;50(9):1240-1246. doi: 10.1038/s41588-018-0191-z. Epub 2018 Aug 20. Nat Genet. 2018. PMID: 30127528 Free PMC article.
Retracted: Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2.
Morita K, He S, Nowak RP, Wang J, Zimmerman MW, Fu C, Durbin AD, Martel MW, Prutsch N, Gray NS, Fischer ES, Look AT. Morita K, et al. Among authors: zimmerman mw. Cell. 2020 Apr 30;181(3):702-715.e20. doi: 10.1016/j.cell.2020.03.051. Epub 2020 Apr 20. Cell. 2020. Retraction in: Cell. 2022 Aug 4;185(16):3058. doi: 10.1016/j.cell.2022.07.008 PMID: 32315619 Free PMC article. Retracted.
40 results