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286 results

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Page 1
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19.
Heard A, Landmann JH, Hansen AR, Papadopolou A, Hsu YS, Selli ME, Warrington JM, Lattin J, Chang J, Ha H, Haug-Kroeper M, Doray B, Gill S, Ruella M, Hayer KE, Weitzman MD, Green AM, Fluhrer R, Singh N. Heard A, et al. Among authors: hansen ar. Nat Commun. 2022 Jun 11;13(1):3367. doi: 10.1038/s41467-022-31035-7. Nat Commun. 2022. PMID: 35690611 Free PMC article.
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress.
O'Leary DR, Hansen AR, Fingerman DF, Tran T, Harris BR, Hayer KE, Fan J, Chen E, Tennakoon M, DeWeerd RA, Meroni A, Szeto JH, Weitzman MD, Shalem O, Bednarski J, Vindigni A, Zhao X, Green AM. O'Leary DR, et al. Among authors: hansen ar. bioRxiv [Preprint]. 2024 Mar 24:2023.11.28.568952. doi: 10.1101/2023.11.28.568952. bioRxiv. 2024. Update in: EMBO J. 2024 Aug;43(15):3240-3255. doi: 10.1038/s44318-024-00137-x PMID: 38077016 Free PMC article. Updated. Preprint.
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress.
Fingerman DF, O'Leary DR, Hansen AR, Tran T, Harris BR, DeWeerd RA, Hayer KE, Fan J, Chen E, Tennakoon M, Meroni A, Szeto JH, Devenport J, LaVigne D, Weitzman MD, Shalem O, Bednarski J, Vindigni A, Zhao X, Green AM. Fingerman DF, et al. Among authors: hansen ar. EMBO J. 2024 Aug;43(15):3240-3255. doi: 10.1038/s44318-024-00137-x. Epub 2024 Jun 17. EMBO J. 2024. PMID: 38886582 Free PMC article.
Pembrolizumab in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) and non-MSI-H/non-dMMR advanced endometrial cancer: Phase 2 KEYNOTE-158 study results.
O'Malley DM, Bariani GM, Cassier PA, Marabelle A, Hansen AR, Acosta AJ, Miller WH Jr, Safra T, Italiano A, Mileshkin L, Yao L, Gozman A, Jin F, Maio M. O'Malley DM, et al. Among authors: hansen ar. Gynecol Oncol. 2025 Jan 22;193:130-135. doi: 10.1016/j.ygyno.2024.12.020. Online ahead of print. Gynecol Oncol. 2025. PMID: 39847999
Initial clinical experience with [177Lu]Lu-PNT2002 radioligand therapy in metastatic castration-resistant prostate cancer: dosimetry, safety, and efficacy from the lead-in cohort of the SPLASH trial.
Hansen AR, Probst S, Beauregard JM, Viglianti BL, Michalski JM, Tagawa ST, Sartor O, Tutrone RF, Oz OK, Courtney KD, Delpassand ES, Nordquist LT, Osman MM, Chi KN, Sparks R, George N, Hawley SM, Wu W, Jensen JD, Fleshner NE. Hansen AR, et al. Front Oncol. 2025 Jan 7;14:1483953. doi: 10.3389/fonc.2024.1483953. eCollection 2024. Front Oncol. 2025. PMID: 39839782 Free PMC article.
A first-in-human study of JNJ-70218902, a bispecific T-cell-redirecting antibody against TMEFF2 in metastatic castration-resistant prostate cancer.
Calvo E, Doger B, Carles J, Peer A, Sarid D, Eigl BJ, Avadhani A, Yao D, Lin V, Wu S, Jaiprasart P, Loffredo J, Tamegnon M, Xu W, Xie H, Hansen AR. Calvo E, et al. Among authors: hansen ar. Oncologist. 2025 Jan 17;30(1):oyae313. doi: 10.1093/oncolo/oyae313. Oncologist. 2025. PMID: 39832129 Free PMC article. Clinical Trial.
Phase Ib Study of the Immunocytokine Simlukafusp Alfa (FAP-IL2v) in Combination with Cetuximab in Patients with Head and Neck Squamous Cell Carcinoma.
Hansen AR, Gomez-Roca CA, Robbrecht DGJ, Verlingue L, Italiano A, Bauman JE, Steeghs N, Prenen H, Fayette J, Spicer J, Niu J, Habigt C, Schneider M, Evers S, Sleiman N, Dejardin D, Ardeshir C, Schmid D, Boetsch C, Charo J, Kraxner A, Teichgräber V, Keshelava N, Bonomi MR. Hansen AR, et al. Clin Cancer Res. 2024 Dec 16;30(24):5540-5547. doi: 10.1158/1078-0432.CCR-24-1562. Clin Cancer Res. 2024. PMID: 39422604 Free PMC article. Clinical Trial.
Advancing patient-centric care: integrating patient reported outcomes for tolerability assessment in early phase clinical trials - insights from an expert virtual roundtable.
Yap C, Lee Aiyegbusi O, Alger E, Basch E, Bell J, Bhatnagar V, Cella D, Collis P, Dueck AC, Gilbert A, Gnanasakthy A, Greystoke A, Hansen AR, Kamudoni P, Kholmanskikh O, King-Kallimanis BL, Krumholz H, Minchom A, O'Connor D, Petrie J, Piccinin C, Rantell KR, Rauz S, Retzer A, Rizk S, Wagner L, Sasseville M, Seymour LK, Weber HA, Wilson R, Calvert M, Peipert JD. Yap C, et al. Among authors: hansen ar. EClinicalMedicine. 2024 Sep 24;76:102838. doi: 10.1016/j.eclinm.2024.102838. eCollection 2024 Oct. EClinicalMedicine. 2024. PMID: 39386161 Free PMC article. Review.
Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab.
Hernando-Calvo A, Yang SYC, Vila-Casadesús M, Han M, Liu ZA, Berman AHK, Spreafico A, Razak AA, Lheureux S, Hansen AR, Lo Giacco D, Abbas-Aghababazadeh F, Matito J, Haibe-Kains B, Pugh TJ, Bratman SV, Aleshin A, Berche R, Saavedra O, Garralda E, Elston S, Siu LL, Ohashi PS, Vivancos A, Bedard PL. Hernando-Calvo A, et al. Among authors: hansen ar. JCO Precis Oncol. 2024 Aug;8:e2400100. doi: 10.1200/PO.24.00100. JCO Precis Oncol. 2024. PMID: 39178369 Free PMC article. Clinical Trial.
286 results