Ory DS - Search Results

1

Validation of Trifluoromethylphenyl Diazirine Cholesterol Analogues As Cholesterol Mimetics and Photolabeling Reagents.

Krishnan K, Qian M, Feltes M, Chen ZW, Gale S, Wang L, Sugasawa Y, Reichert DE, Schaffer JE, Ory DS, Evers AS, Covey DF. Krishnan K, et al. Among authors: ory ds. ACS Chem Biol. 2021 Aug 20;16(8):1493-1507. doi: 10.1021/acschembio.1c00364. Epub 2021 Aug 6. ACS Chem Biol. 2021. PMID: 34355883 Free PMC article.

2

The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol.

Millard EE, Gale SE, Dudley N, Zhang J, Schaffer JE, Ory DS. Millard EE, et al. Among authors: ory ds. J Biol Chem. 2005 Aug 5;280(31):28581-90. doi: 10.1074/jbc.M414024200. Epub 2005 May 20. J Biol Chem. 2005. PMID: 15908696 Free article.

3

Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease.

Langmade SJ, Gale SE, Frolov A, Mohri I, Suzuki K, Mellon SH, Walkley SU, Covey DF, Schaffer JE, Ory DS. Langmade SJ, et al. Among authors: ory ds. Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13807-12. doi: 10.1073/pnas.0606218103. Epub 2006 Aug 29. Proc Natl Acad Sci U S A. 2006. PMID: 16940355 Free PMC article.

4

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death.

Borradaile NM, Han X, Harp JD, Gale SE, Ory DS, Schaffer JE. Borradaile NM, et al. Among authors: ory ds. J Lipid Res. 2006 Dec;47(12):2726-37. doi: 10.1194/jlr.M600299-JLR200. Epub 2006 Sep 7. J Lipid Res. 2006. PMID: 16960261 Free article.

5

Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding.

Gelsthorpe ME, Baumann N, Millard E, Gale SE, Langmade SJ, Schaffer JE, Ory DS. Gelsthorpe ME, et al. Among authors: ory ds. J Biol Chem. 2008 Mar 28;283(13):8229-36. doi: 10.1074/jbc.M708735200. Epub 2008 Jan 23. J Biol Chem. 2008. PMID: 18216017 Free PMC article.

6

Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.

Gale SE, Westover EJ, Dudley N, Krishnan K, Merlin S, Scherrer DE, Han X, Zhai X, Brockman HL, Brown RE, Covey DF, Schaffer JE, Schlesinger P, Ory DS. Gale SE, et al. Among authors: ory ds. J Biol Chem. 2009 Jan 16;284(3):1755-64. doi: 10.1074/jbc.M807210200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18996837 Free PMC article.

7

ApoA-1 in diabetes: damaged goods.

Ory DS, Schaffer JE. Ory DS, et al. Diabetes. 2010 Oct;59(10):2358-9. doi: 10.2337/db10-1040. Diabetes. 2010. PMID: 20876728 Free PMC article. No abstract available.

8

Synthesis of the enantiomer of the oxysterol-antagonist LY295427.

Bielska AA, Ory DS, Covey DF. Bielska AA, et al. Among authors: ory ds. Steroids. 2011 Sep-Oct;76(10-11):986-90. doi: 10.1016/j.steroids.2011.03.008. Epub 2011 Apr 4. Steroids. 2011. PMID: 21470559 Free PMC article.

9

Oxysterols as non-genomic regulators of cholesterol homeostasis.

Bielska AA, Schlesinger P, Covey DF, Ory DS. Bielska AA, et al. Among authors: ory ds. Trends Endocrinol Metab. 2012 Mar;23(3):99-106. doi: 10.1016/j.tem.2011.12.002. Epub 2012 Jan 11. Trends Endocrinol Metab. 2012. PMID: 22244444 Free PMC article.

10

SmD3 regulates intronic noncoding RNA biogenesis.

Scruggs BS, Michel CI, Ory DS, Schaffer JE. Scruggs BS, et al. Among authors: ory ds. Mol Cell Biol. 2012 Oct;32(20):4092-103. doi: 10.1128/MCB.00022-12. Epub 2012 Aug 6. Mol Cell Biol. 2012. PMID: 22869524 Free PMC article.

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