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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
Tarantini S, Nyúl-Tóth Á, Yabluchanskiy A, Csipo T, Mukli P, Balasubramanian P, Ungvari A, Toth P, Benyo Z, Sonntag WE, Ungvari Z, Csiszar A. Tarantini S, et al. Among authors: mukli p. Geroscience. 2021 Oct;43(5):2387-2394. doi: 10.1007/s11357-021-00405-2. Epub 2021 Aug 12. Geroscience. 2021. PMID: 34383203 Free PMC article.
Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans.
Csipo T, Mukli P, Lipecz A, Tarantini S, Bahadli D, Abdulhussein O, Owens C, Kiss T, Balasubramanian P, Nyúl-Tóth Á, Hand RA, Yabluchanska V, Sorond FA, Csiszar A, Ungvari Z, Yabluchanskiy A. Csipo T, et al. Among authors: mukli p. Geroscience. 2019 Oct;41(5):495-509. doi: 10.1007/s11357-019-00122-x. Epub 2019 Nov 2. Geroscience. 2019. PMID: 31676966 Free PMC article. Review.
Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults.
Csipo T, Lipecz A, Mukli P, Bahadli D, Abdulhussein O, Owens CD, Tarantini S, Hand RA, Yabluchanska V, Kellawan JM, Sorond F, James JA, Csiszar A, Ungvari ZI, Yabluchanskiy A. Csipo T, et al. Among authors: mukli p. PLoS One. 2021 May 19;16(5):e0250043. doi: 10.1371/journal.pone.0250043. eCollection 2021. PLoS One. 2021. PMID: 34010279 Free PMC article.
Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
Tarantini S, Balasubramanian P, Delfavero J, Csipo T, Yabluchanskiy A, Kiss T, Nyúl-Tóth Á, Mukli P, Toth P, Ahire C, Ungvari A, Benyo Z, Csiszar A, Ungvari Z. Tarantini S, et al. Among authors: mukli p. Geroscience. 2021 Oct;43(5):2427-2440. doi: 10.1007/s11357-021-00440-z. Epub 2021 Aug 24. Geroscience. 2021. PMID: 34427858 Free PMC article.
Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.
Csipo T, Lipecz A, Owens C, Mukli P, Perry JW, Tarantini S, Balasubramanian P, Nyúl-Tóth Á, Yabluchanska V, Sorond FA, Kellawan JM, Purebl G, Sonntag WE, Csiszar A, Ungvari Z, Yabluchanskiy A. Csipo T, et al. Among authors: mukli p. Sci Rep. 2021 Oct 25;11(1):20994. doi: 10.1038/s41598-021-00188-8. Sci Rep. 2021. PMID: 34697326 Free PMC article.
Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling.
Kiss T, Nyúl-Tóth Á, Gulej R, Tarantini S, Csipo T, Mukli P, Ungvari A, Balasubramanian P, Yabluchanskiy A, Benyo Z, Conley SM, Wren JD, Garman L, Huffman DM, Csiszar A, Ungvari Z. Kiss T, et al. Among authors: mukli p. Geroscience. 2022 Apr;44(2):953-981. doi: 10.1007/s11357-022-00519-1. Epub 2022 Feb 5. Geroscience. 2022. PMID: 35124764 Free PMC article.
Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
Owens CD, Mukli P, Csipo T, Lipecz A, Silva-Palacios F, Dasari TW, Tarantini S, Gardner AW, Montgomery PS, Waldstein SR, Kellawan JM, Nyul-Toth A, Balasubramanian P, Sotonyi P, Csiszar A, Ungvari Z, Yabluchanskiy A. Owens CD, et al. Among authors: mukli p. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H924-H935. doi: 10.1152/ajpheart.00616.2021. Epub 2022 Mar 25. Am J Physiol Heart Circ Physiol. 2022. PMID: 35333116 Free PMC article.
61 results