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Dietary fructose improves intestinal cell survival and nutrient absorption.
Taylor SR, Ramsamooj S, Liang RJ, Katti A, Pozovskiy R, Vasan N, Hwang SK, Nahiyaan N, Francoeur NJ, Schatoff EM, Johnson JL, Shah MA, Dannenberg AJ, Sebra RP, Dow LE, Cantley LC, Rhee KY, Goncalves MD. Taylor SR, et al. Among authors: goncalves md. Nature. 2021 Sep;597(7875):263-267. doi: 10.1038/s41586-021-03827-2. Epub 2021 Aug 18. Nature. 2021. PMID: 34408323 Free PMC article.
Obesity and Cancer Mechanisms: Cancer Metabolism.
Hopkins BD, Goncalves MD, Cantley LC. Hopkins BD, et al. Among authors: goncalves md. J Clin Oncol. 2016 Dec 10;34(35):4277-4283. doi: 10.1200/JCO.2016.67.9712. Epub 2016 Nov 7. J Clin Oncol. 2016. PMID: 27903152 Free PMC article. Review.
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Goncalves MD, Hwang SK, Pauli C, Murphy CJ, Cheng Z, Hopkins BD, Wu D, Loughran RM, Emerling BM, Zhang G, Fearon DT, Cantley LC. Goncalves MD, et al. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E743-E752. doi: 10.1073/pnas.1714703115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311302 Free PMC article.
Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Lundquist MR, Goncalves MD, Loughran RM, Possik E, Vijayaraghavan T, Yang A, Pauli C, Ravi A, Verma A, Yang Z, Johnson JL, Wong JCY, Ma Y, Hwang KS, Weinkove D, Divecha N, Asara JM, Elemento O, Rubin MA, Kimmelman AC, Pause A, Cantley LC, Emerling BM. Lundquist MR, et al. Among authors: goncalves md. Mol Cell. 2018 May 3;70(3):531-544.e9. doi: 10.1016/j.molcel.2018.03.037. Mol Cell. 2018. PMID: 29727621 Free PMC article.
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors.
Hopkins BD, Pauli C, Du X, Wang DG, Li X, Wu D, Amadiume SC, Goncalves MD, Hodakoski C, Lundquist MR, Bareja R, Ma Y, Harris EM, Sboner A, Beltran H, Rubin MA, Mukherjee S, Cantley LC. Hopkins BD, et al. Among authors: goncalves md. Nature. 2018 Aug;560(7719):499-503. doi: 10.1038/s41586-018-0343-4. Epub 2018 Jul 4. Nature. 2018. PMID: 30051890 Free PMC article.
High-fructose corn syrup enhances intestinal tumor growth in mice.
Goncalves MD, Lu C, Tutnauer J, Hartman TE, Hwang SK, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K, Yang S, Wang Y, Van Riper J, Lekaye HC, Roper J, Kim Y, Chen Q, Gross SS, Rhee KY, Cantley LC, Yun J. Goncalves MD, et al. Science. 2019 Mar 22;363(6433):1345-1349. doi: 10.1126/science.aat8515. Science. 2019. PMID: 30898933 Free PMC article.
145 results