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Dietary fructose improves intestinal cell survival and nutrient absorption.
Taylor SR, Ramsamooj S, Liang RJ, Katti A, Pozovskiy R, Vasan N, Hwang SK, Nahiyaan N, Francoeur NJ, Schatoff EM, Johnson JL, Shah MA, Dannenberg AJ, Sebra RP, Dow LE, Cantley LC, Rhee KY, Goncalves MD. Taylor SR, et al. Among authors: hwang sk. Nature. 2021 Sep;597(7875):263-267. doi: 10.1038/s41586-021-03827-2. Epub 2021 Aug 18. Nature. 2021. PMID: 34408323 Free PMC article.
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Goncalves MD, Hwang SK, Pauli C, Murphy CJ, Cheng Z, Hopkins BD, Wu D, Loughran RM, Emerling BM, Zhang G, Fearon DT, Cantley LC. Goncalves MD, et al. Among authors: hwang sk. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E743-E752. doi: 10.1073/pnas.1714703115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311302 Free PMC article.
High-fructose corn syrup enhances intestinal tumor growth in mice.
Goncalves MD, Lu C, Tutnauer J, Hartman TE, Hwang SK, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K, Yang S, Wang Y, Van Riper J, Lekaye HC, Roper J, Kim Y, Chen Q, Gross SS, Rhee KY, Cantley LC, Yun J. Goncalves MD, et al. Among authors: hwang sk. Science. 2019 Mar 22;363(6433):1345-1349. doi: 10.1126/science.aat8515. Science. 2019. PMID: 30898933 Free PMC article.
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase.
Liang RJ, Taylor S, Nahiyaan N, Song J, Murphy CJ, Dantas E, Cheng S, Hsu TW, Ramsamooj S, Grover R, Hwang SK, Ngo B, Cantley LC, Rhee KY, Goncalves MD. Liang RJ, et al. Among authors: hwang sk. Cancer Metab. 2021 Mar 24;9(1):12. doi: 10.1186/s40170-021-00246-9. Cancer Metab. 2021. PMID: 33762003 Free PMC article.
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.
Langer HT, Ramsamooj S, Dantas E, Murthy A, Ahmed M, Hwang SK, Grover R, Pozovskiy R, Liang RJ, Queiroz AL, Brown JC, White EP, Janowitz T, Goncalves AMD. Langer HT, et al. Among authors: hwang sk. bioRxiv [Preprint]. 2023 Aug 2:2023.07.31.551241. doi: 10.1101/2023.07.31.551241. bioRxiv. 2023. Update in: Acta Physiol (Oxf). 2024 Aug;240(8):e14167. doi: 10.1111/apha.14167 PMID: 37577571 Free PMC article. Updated. Preprint.
Epinephrine inhibits PI3Kα via the Hippo kinases.
Lin TY, Ramsamooj S, Perrier T, Liberatore K, Lantier L, Vasan N, Karukurichi K, Hwang SK, Kesicki EA, Kastenhuber ER, Wiederhold T, Yaron TM, Huntsman EM, Zhu M, Ma Y, Paddock MN, Zhang G, Hopkins BD, McGuinness O, Schwartz RE, Ersoy BA, Cantley LC, Johnson JL, Goncalves MD. Lin TY, et al. Among authors: hwang sk. Cell Rep. 2023 Dec 26;42(12):113535. doi: 10.1016/j.celrep.2023.113535. Epub 2023 Dec 4. Cell Rep. 2023. PMID: 38060450 Free PMC article.
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.
Langer HT, Ramsamooj S, Dantas E, Murthy A, Ahmed M, Ahmed T, Hwang SK, Grover R, Pozovskiy R, Liang RJ, Queiroz AL, Brown JC, White EP, Janowitz T, Goncalves MD. Langer HT, et al. Among authors: hwang sk. Acta Physiol (Oxf). 2024 Aug;240(8):e14167. doi: 10.1111/apha.14167. Epub 2024 May 23. Acta Physiol (Oxf). 2024. PMID: 38779820
394 results