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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Among authors: bourke nm. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Control of HIV infection by IFN-α: implications for latency and a cure.
Bourke NM, Napoletano S, Bannan C, Ahmed S, Bergin C, McKnight Á, Stevenson NJ. Bourke NM, et al. Cell Mol Life Sci. 2018 Mar;75(5):775-783. doi: 10.1007/s00018-017-2652-4. Epub 2017 Oct 7. Cell Mol Life Sci. 2018. PMID: 28988399 Free PMC article. Review.
Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection.
Townsend L, Dyer AH, Jones K, Dunne J, Mooney A, Gaffney F, O'Connor L, Leavy D, O'Brien K, Dowds J, Sugrue JA, Hopkins D, Martin-Loeches I, Ni Cheallaigh C, Nadarajan P, McLaughlin AM, Bourke NM, Bergin C, O'Farrelly C, Bannan C, Conlon N. Townsend L, et al. Among authors: bourke nm. PLoS One. 2020 Nov 9;15(11):e0240784. doi: 10.1371/journal.pone.0240784. eCollection 2020. PLoS One. 2020. PMID: 33166287 Free PMC article.
Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity.
Townsend L, Dowds J, O'Brien K, Sheill G, Dyer AH, O'Kelly B, Hynes JP, Mooney A, Dunne J, Ni Cheallaigh C, O'Farrelly C, Bourke NM, Conlon N, Martin-Loeches I, Bergin C, Nadarajan P, Bannan C. Townsend L, et al. Among authors: bourke nm. Ann Am Thorac Soc. 2021 Jun;18(6):997-1003. doi: 10.1513/AnnalsATS.202009-1175OC. Ann Am Thorac Soc. 2021. PMID: 33413026 Free PMC article.
Peripheral Inflammation and Cognitive Performance in Middle-Aged Adults With and Without Type 2 Diabetes: Results From the ENBIND Study.
Dyer AH, McKenna L, Batten I, Jones K, Widdowson M, Dunne J, Conlon N, Reilly R, Woods CP, O'Neill D, Gibney J, Bourke NM, Kennelly SP. Dyer AH, et al. Among authors: bourke nm. Front Aging Neurosci. 2020 Nov 30;12:605878. doi: 10.3389/fnagi.2020.605878. eCollection 2020. Front Aging Neurosci. 2020. PMID: 33424582 Free PMC article.
Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response.
Townsend L, Fogarty H, Dyer A, Martin-Loeches I, Bannan C, Nadarajan P, Bergin C, O'Farrelly C, Conlon N, Bourke NM, Ward SE, Byrne M, Ryan K, O'Connell N, O'Sullivan JM, Ni Cheallaigh C, O'Donnell JS. Townsend L, et al. Among authors: bourke nm. J Thromb Haemost. 2021 Apr;19(4):1064-1070. doi: 10.1111/jth.15267. Epub 2021 Mar 8. J Thromb Haemost. 2021. PMID: 33587810 Free PMC article.
42 results