Morari M - Search Results

1

Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo.

Albanese F, Mercatelli D, Finetti L, Lamonaca G, Pizzi S, Shimshek DR, Bernacchia G, Morari M. Albanese F, et al. Among authors: morari m. Neurobiol Dis. 2021 Nov;159:105487. doi: 10.1016/j.nbd.2021.105487. Epub 2021 Aug 20. Neurobiol Dis. 2021. PMID: 34419621 Free article.

2

In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels.

Mela F, Marti M, Bido S, Cenci MA, Morari M. Mela F, et al. Among authors: morari m. Neurobiol Dis. 2012 Jan;45(1):573-82. doi: 10.1016/j.nbd.2011.09.015. Epub 2011 Oct 7. Neurobiol Dis. 2012. PMID: 22001605

3

Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging.

Longo F, Russo I, Shimshek DR, Greggio E, Morari M. Longo F, et al. Among authors: morari m. Neurobiol Dis. 2014 Nov;71:62-73. doi: 10.1016/j.nbd.2014.07.013. Epub 2014 Aug 6. Neurobiol Dis. 2014. PMID: 25107341 Free PMC article.

4

Eltoprazine prevents levodopa-induced dyskinesias by reducing striatal glutamate and direct pathway activity.

Paolone G, Brugnoli A, Arcuri L, Mercatelli D, Morari M. Paolone G, et al. Among authors: morari m. Mov Disord. 2015 Nov;30(13):1728-38. doi: 10.1002/mds.26326. Epub 2015 Jul 24. Mov Disord. 2015. PMID: 26207892

5

Genetic deletion of Rhes or pharmacological blockade of mTORC1 prevent striato-nigral neurons activation in levodopa-induced dyskinesia.

Brugnoli A, Napolitano F, Usiello A, Morari M. Brugnoli A, et al. Among authors: morari m. Neurobiol Dis. 2016 Jan;85:155-163. doi: 10.1016/j.nbd.2015.10.020. Epub 2015 Oct 29. Neurobiol Dis. 2016. PMID: 26522958

6

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.

Arcuri L, Viaro R, Bido S, Longo F, Calcagno M, Fernagut PO, Zaveri NT, Calò G, Bezard E, Morari M. Arcuri L, et al. Among authors: morari m. Neurobiol Dis. 2016 May;89:55-64. doi: 10.1016/j.nbd.2016.01.016. Epub 2016 Jan 22. Neurobiol Dis. 2016. PMID: 26804029 Free PMC article.

7

Parkinson's disease: no NOP, new hope.

Arcuri L, Mercatelli D, Morari M. Arcuri L, et al. Among authors: morari m. Oncotarget. 2017 Feb 7;8(6):8995-8996. doi: 10.18632/oncotarget.13710. Oncotarget. 2017. PMID: 28086211 Free PMC article. No abstract available.

8

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice.

Longo F, Mercatelli D, Novello S, Arcuri L, Brugnoli A, Vincenzi F, Russo I, Berti G, Mabrouk OS, Kennedy RT, Shimshek DR, Varani K, Bubacco L, Greggio E, Morari M. Longo F, et al. Among authors: morari m. Acta Neuropathol Commun. 2017 Mar 14;5(1):22. doi: 10.1186/s40478-017-0426-8. Acta Neuropathol Commun. 2017. PMID: 28292328 Free PMC article.

9

Anti-Parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists.

Arcuri L, Novello S, Frassineti M, Mercatelli D, Pisanò CA, Morella I, Fasano S, Journigan BV, Meyer ME, Polgar WE, Brambilla R, Zaveri NT, Morari M. Arcuri L, et al. Among authors: morari m. Br J Pharmacol. 2018 Mar;175(5):782-796. doi: 10.1111/bph.14123. Epub 2018 Jan 31. Br J Pharmacol. 2018. PMID: 29232769 Free PMC article.

10

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease.

Tozzi A, Tantucci M, Marchi S, Mazzocchetti P, Morari M, Pinton P, Mancini A, Calabresi P. Tozzi A, et al. Among authors: morari m. Cell Death Dis. 2018 Feb 12;9(2):204. doi: 10.1038/s41419-017-0221-2. Cell Death Dis. 2018. PMID: 29434188 Free PMC article.

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