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An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Naninck T, Kahlaoui N, Lemaitre J, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Contreras V, Marlin R, Tsong Fang RH, Chapon C, van der Werf S, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Le Grand R, Vandenberghe LH. Zabaleta N, et al. Among authors: griffiths a. Cell Host Microbe. 2021 Sep 8;29(9):1437-1453.e8. doi: 10.1016/j.chom.2021.08.002. Epub 2021 Aug 7. Cell Host Microbe. 2021. PMID: 34428428 Free PMC article.
Cellular Nanosponges Inhibit SARS-CoV-2 Infectivity.
Zhang Q, Honko A, Zhou J, Gong H, Downs SN, Vasquez JH, Fang RH, Gao W, Griffiths A, Zhang L. Zhang Q, et al. Among authors: griffiths a. Nano Lett. 2020 Jul 8;20(7):5570-5574. doi: 10.1021/acs.nanolett.0c02278. Epub 2020 Jun 17. Nano Lett. 2020. PMID: 32551679 Free article.
Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022.
Atyeo C, Slein MD, Fischinger S, Burke J, Schäfer A, Leist SR, Kuzmina NA, Mire C, Honko A, Johnson R, Storm N, Bernett M, Tong P, Zuo T, Lin J, Zuiani A, Linde C, Suscovich T, Wesemann DR, Griffiths A, Desjarlais JR, Juelg BD, Goudsmit J, Bukreyev A, Baric R, Alter G. Atyeo C, et al. Among authors: griffiths a. JCI Insight. 2021 Jan 11;6(1):e143129. doi: 10.1172/jci.insight.143129. JCI Insight. 2021. PMID: 33427208 Free PMC article.
A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. Xiao T, et al. Among authors: griffiths a. Nat Struct Mol Biol. 2021 Feb;28(2):202-209. doi: 10.1038/s41594-020-00549-3. Epub 2021 Jan 11. Nat Struct Mol Biol. 2021. PMID: 33432247 Free PMC article.
Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates.
Zabaleta N, Dai W, Bhatt U, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Vandenberghe LH. Zabaleta N, et al. Among authors: griffiths a. bioRxiv [Preprint]. 2021 Jan 19:2021.01.05.422952. doi: 10.1101/2021.01.05.422952. bioRxiv. 2021. Update in: Cell Host Microbe. 2021 Sep 8;29(9):1437-1453.e8. doi: 10.1016/j.chom.2021.08.002 PMID: 33442684 Free PMC article. Updated. Preprint.
Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival.
Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz ÖH, Kwon DS. Das Adhikari U, et al. Among authors: griffiths a. Clin Infect Dis. 2022 Mar 23;74(6):1081-1084. doi: 10.1093/cid/ciab623. Clin Infect Dis. 2022. PMID: 34245255 Free PMC article.
1,515 results