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An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Naninck T, Kahlaoui N, Lemaitre J, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Contreras V, Marlin R, Tsong Fang RH, Chapon C, van der Werf S, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Le Grand R, Vandenberghe LH. Zabaleta N, et al. Among authors: le grand r. Cell Host Microbe. 2021 Sep 8;29(9):1437-1453.e8. doi: 10.1016/j.chom.2021.08.002. Epub 2021 Aug 7. Cell Host Microbe. 2021. PMID: 34428428 Free PMC article.
CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates.
Romain G, van Gulck E, Epaulard O, Oh S, Li D, Zurawski G, Zurawski S, Cosma A, Adam L, Chapon C, Todorova B, Banchereau J, Dereuddre-Bosquet N, Vanham G, Le Grand R, Martinon F. Romain G, et al. Among authors: le grand r. Eur J Immunol. 2012 Aug;42(8):2019-30. doi: 10.1002/eji.201242478. Epub 2012 Jul 4. Eur J Immunol. 2012. PMID: 22585548 Free PMC article.
MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques.
Dereuddre-Bosquet N, Morellato-Castillo L, Brouwers J, Augustijns P, Bouchemal K, Ponchel G, Ramos OH, Herrera C, Stefanidou M, Shattock R, Heyndrickx L, Vanham G, Kessler P, Le Grand R, Martin L. Dereuddre-Bosquet N, et al. Among authors: le grand r. PLoS Pathog. 2012;8(12):e1003071. doi: 10.1371/journal.ppat.1003071. Epub 2012 Dec 6. PLoS Pathog. 2012. PMID: 23236282 Free PMC article.
Macrophage- and neutrophil-derived TNF-α instructs skin langerhans cells to prime antiviral immune responses.
Epaulard O, Adam L, Poux C, Zurawski G, Salabert N, Rosenbaum P, Dereuddre-Bosquet N, Zurawski S, Flamar AL, Oh S, Romain G, Chapon C, Banchereau J, Lévy Y, Le Grand R, Martinon F. Epaulard O, et al. Among authors: le grand r. J Immunol. 2014 Sep 1;193(5):2416-26. doi: 10.4049/jimmunol.1303339. Epub 2014 Jul 23. J Immunol. 2014. PMID: 25057007 Free PMC article.
Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses.
Bruel T, Hamimi C, Dereuddre-Bosquet N, Cosma A, Shin SY, Corneau A, Versmisse P, Karlsson I, Malleret B, Targat B, Barré-Sinoussi F, Le Grand R, Pancino G, Sáez-Cirión A, Vaslin B. Bruel T, et al. Among authors: le grand r. J Virol. 2015 Apr;89(7):3542-56. doi: 10.1128/JVI.03723-14. Epub 2015 Jan 14. J Virol. 2015. PMID: 25589645 Free PMC article.
360 results