Locke E - Search Results

1

Multiplex serological assay for establishing serological profiles of polymorphic, closely related peptide antigens.

Bolton J, Chaudhury S, MacGill RS, Early AM, King CR, Locke E, Neafsey DE, Bergmann-Leitner ES. Bolton J, et al. Among authors: locke e. MethodsX. 2021 Apr 22;8:101345. doi: 10.1016/j.mex.2021.101345. eCollection 2021. MethodsX. 2021. PMID: 34430249 Free PMC article.

2

Comparison of ELISA with electro-chemiluminescence technology for the qualitative and quantitative assessment of serological responses to vaccination.

Bolton JS, Chaudhury S, Dutta S, Gregory S, Locke E, Pierson T, Bergmann-Leitner ES. Bolton JS, et al. Among authors: locke e. Malar J. 2020 Apr 17;19(1):159. doi: 10.1186/s12936-020-03225-5. Malar J. 2020. PMID: 32303235 Free PMC article.

3

Breadth of humoral immune responses to the C-terminus of the circumsporozoite protein is associated with protective efficacy induced by the RTS,S malaria vaccine.

Chaudhury S, MacGill RS, Early AM, Bolton JS, King CR, Locke E, Pierson T, Wirth DF, Neafsey DE, Bergmann-Leitner ES. Chaudhury S, et al. Among authors: locke e. Vaccine. 2021 Feb 5;39(6):968-975. doi: 10.1016/j.vaccine.2020.12.055. Epub 2021 Jan 9. Vaccine. 2021. PMID: 33431225 Free article.

4

A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.

Beutler N, Pholcharee T, Oyen D, Flores-Garcia Y, MacGill RS, Garcia E, Calla J, Parren M, Yang L, Volkmuth W, Locke E, Regules JA, Dutta S, Emerling D, Early AM, Neafsey DE, Winzeler EA, King CR, Zavala F, Burton DR, Wilson IA, Rogers TF. Beutler N, et al. Among authors: locke e. PLoS Pathog. 2022 Mar 28;18(3):e1010409. doi: 10.1371/journal.ppat.1010409. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35344575 Free PMC article.

5

Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages.

Flores-Garcia Y, Herrera SM, Jhun H, Pérez-Ramos DW, King CR, Locke E, Raghunandan R, Zavala F. Flores-Garcia Y, et al. Among authors: locke e. Malar J. 2019 Dec 18;18(1):426. doi: 10.1186/s12936-019-3055-9. Malar J. 2019. PMID: 31849326 Free PMC article.

6

Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein.

Raghunandan R, Mayer BT, Flores-Garcia Y, Gerber MW, Gottardo R, Jhun H, Herrera SM, Perez-Ramos DW, Locke E, King CR, Zavala F. Raghunandan R, et al. Among authors: locke e. Malar J. 2020 Mar 17;19(1):113. doi: 10.1186/s12936-020-03181-0. Malar J. 2020. PMID: 32183833 Free PMC article.

7

Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein.

Pholcharee T, Oyen D, Torres JL, Flores-Garcia Y, Martin GM, González-Páez GE, Emerling D, Volkmuth W, Locke E, King CR, Zavala F, Ward AB, Wilson IA. Pholcharee T, et al. Among authors: locke e. J Mol Biol. 2020 Feb 14;432(4):1048-1063. doi: 10.1016/j.jmb.2019.12.029. Epub 2019 Dec 27. J Mol Biol. 2020. PMID: 31883801 Free PMC article.

8

Vaccine co-display of CSP and Pfs230 on liposomes targeting two Plasmodium falciparum differentiation stages.

Huang WC, Mabrouk MT, Zhou L, Baba M, Tachibana M, Torii M, Takashima E, Locke E, Plieskatt J, King CR, Coelho CH, Duffy PE, Long C, Tsuboi T, Miura K, Wu Y, Ishino T, Lovell JF. Huang WC, et al. Among authors: locke e. Commun Biol. 2022 Aug 1;5(1):773. doi: 10.1038/s42003-022-03688-z. Commun Biol. 2022. PMID: 35915227 Free PMC article.

9

The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable.

Singh SK, Plieskatt J, Chourasia BK, Singh V, Bolscher JM, Dechering KJ, Adu B, López-Méndez B, Kaviraj S, Locke E, King CR, Theisen M. Singh SK, et al. Among authors: locke e. J Biol Chem. 2020 Jan 10;295(2):403-414. doi: 10.1074/jbc.RA119.011268. Epub 2019 Dec 2. J Biol Chem. 2020. PMID: 31792057 Free PMC article.

10

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.

Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter Š, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, Kellam P, Zavala F, Ward AB, Wilson IA. Oyen D, et al. Among authors: locke e. PLoS Pathog. 2020 Mar 9;16(3):e1008373. doi: 10.1371/journal.ppat.1008373. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32150583 Free PMC article.

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