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Structured elements drive extensive circular RNA translation.
Chen CK, Cheng R, Demeter J, Chen J, Weingarten-Gabbay S, Jiang L, Snyder MP, Weissman JS, Segal E, Jackson PK, Chang HY. Chen CK, et al. Among authors: weissman js. Mol Cell. 2021 Oct 21;81(20):4300-4318.e13. doi: 10.1016/j.molcel.2021.07.042. Epub 2021 Aug 25. Mol Cell. 2021. PMID: 34437836 Free PMC article.
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.
Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA. Liu SJ, et al. Among authors: weissman js. Science. 2017 Jan 6;355(6320):aah7111. doi: 10.1126/science.aah7111. Epub 2016 Dec 15. Science. 2017. PMID: 27980086 Free PMC article.
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.
Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, Weissman JS, Curtis C, Chang HY. Cho SW, et al. Among authors: weissman js. Cell. 2018 May 31;173(6):1398-1412.e22. doi: 10.1016/j.cell.2018.03.068. Epub 2018 May 3. Cell. 2018. PMID: 29731168 Free PMC article.
Ribosome Profiling: Global Views of Translation.
Ingolia NT, Hussmann JA, Weissman JS. Ingolia NT, et al. Among authors: weissman js. Cold Spring Harb Perspect Biol. 2019 May 1;11(5):a032698. doi: 10.1101/cshperspect.a032698. Cold Spring Harb Perspect Biol. 2019. PMID: 30037969 Free PMC article. Review.
Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes.
Horlbeck MA, Liu SJ, Chang HY, Lim DA, Weissman JS. Horlbeck MA, et al. Among authors: weissman js. Nat Biotechnol. 2020 May;38(5):573-576. doi: 10.1038/s41587-020-0428-0. Epub 2020 Feb 24. Nat Biotechnol. 2020. PMID: 32094656 Free PMC article. No abstract available.
Pervasive functional translation of noncanonical human open reading frames.
Chen J, Brunner AD, Cogan JZ, Nuñez JK, Fields AP, Adamson B, Itzhak DN, Li JY, Mann M, Leonetti MD, Weissman JS. Chen J, et al. Among authors: weissman js. Science. 2020 Mar 6;367(6482):1140-1146. doi: 10.1126/science.aay0262. Science. 2020. PMID: 32139545 Free PMC article.
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. Replogle JM, et al. Among authors: weissman js. Nat Biotechnol. 2020 Aug;38(8):954-961. doi: 10.1038/s41587-020-0470-y. Epub 2020 Mar 30. Nat Biotechnol. 2020. PMID: 32231336 Free PMC article.
A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation.
Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, Chen J, Shmulevich I, Weissman JS, Curtis C, Califano A, Fu H, Crabtree GR, Kuo CJ. Lo YH, et al. Among authors: weissman js. Cancer Discov. 2021 Jun;11(6):1562-1581. doi: 10.1158/2159-8290.CD-20-1109. Epub 2021 Jan 15. Cancer Discov. 2021. PMID: 33451982 Free PMC article.
Regulation of translation by methylation multiplicity of 18S rRNA.
Liu K, Santos DA, Hussmann JA, Wang Y, Sutter BM, Weissman JS, Tu BP. Liu K, et al. Among authors: weissman js. Cell Rep. 2021 Mar 9;34(10):108825. doi: 10.1016/j.celrep.2021.108825. Cell Rep. 2021. PMID: 33691096 Free PMC article.
568 results