Karn J - Search Results

1

Oral immune dysfunction is associated with the expansion of FOXP3⁺PD-1⁺Amphiregulin⁺ T cells during HIV infection.

Bhaskaran N, Schneider E, Faddoul F, Paes da Silva A, Asaad R, Talla A, Greenspan N, Levine AD, McDonald D, Karn J, Lederman MM, Pandiyan P. Bhaskaran N, et al. Among authors: karn j. Nat Commun. 2021 Aug 26;12(1):5143. doi: 10.1038/s41467-021-25340-w. Nat Commun. 2021. PMID: 34446704 Free PMC article.

2

Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA.

Chen L, Feng Z, Yue H, Bazdar D, Mbonye U, Zender C, Harding CV, Bruggeman L, Karn J, Sieg SF, Wang B, Jin G. Chen L, et al. Among authors: karn j. Nat Commun. 2018 Nov 2;9(1):4585. doi: 10.1038/s41467-018-07006-2. Nat Commun. 2018. PMID: 30389917 Free PMC article.

3

Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.

Mbonye U, Leskov K, Shukla M, Valadkhan S, Karn J. Mbonye U, et al. Among authors: karn j. PLoS Pathog. 2021 Sep 16;17(9):e1009581. doi: 10.1371/journal.ppat.1009581. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34529720 Free PMC article.

4

Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda.

Joussef-Piña S, Nankya I, Nalukwago S, Baseke J, Rwambuya S, Winner D, Kyeyune F, Chervenak K, Thiel B, Asaad R, Dobrowolski C, Luttge B, Lawley B, Kityo CM, Boom WH, Karn J, Quiñones-Mateu ME. Joussef-Piña S, et al. Among authors: karn j. Retrovirology. 2022 Jan 15;19(1):1. doi: 10.1186/s12977-022-00587-3. Retrovirology. 2022. PMID: 35033105 Free PMC article.

5

Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.

Miller JS, Davis ZB, Helgeson E, Reilly C, Thorkelson A, Anderson J, Lima NS, Jorstad S, Hart GT, Lee JH, Safrit JT, Wong H, Cooley S, Gharu L, Chung H, Soon-Shiong P, Dobrowolski C, Fletcher CV, Karn J, Douek DC, Schacker TW. Miller JS, et al. Among authors: karn j. Nat Med. 2022 Feb;28(2):392-400. doi: 10.1038/s41591-021-01651-9. Epub 2022 Jan 31. Nat Med. 2022. PMID: 35102335 Clinical Trial.

6

The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events.

Lucera MB, Tilton CA, Mao H, Dobrowolski C, Tabler CO, Haqqani AA, Karn J, Tilton JC. Lucera MB, et al. Among authors: karn j. J Virol. 2014 Sep;88(18):10803-12. doi: 10.1128/JVI.00320-14. Epub 2014 Jul 9. J Virol. 2014. PMID: 25008921 Free PMC article.

7

Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing.

Kaminski R, Chen Y, Fischer T, Tedaldi E, Napoli A, Zhang Y, Karn J, Hu W, Khalili K. Kaminski R, et al. Among authors: karn j. Sci Rep. 2016 Mar 4;6:22555. doi: 10.1038/srep22555. Sci Rep. 2016. PMID: 26939770 Free PMC article.

8

Negative Feedback Regulation of HIV-1 by Gene Editing Strategy.

Kaminski R, Chen Y, Salkind J, Bella R, Young WB, Ferrante P, Karn J, Malcolm T, Hu W, Khalili K. Kaminski R, et al. Among authors: karn j. Sci Rep. 2016 Aug 16;6:31527. doi: 10.1038/srep31527. Sci Rep. 2016. PMID: 27528385 Free PMC article.

9

Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells.

Alvarez-Carbonell D, Garcia-Mesa Y, Milne S, Das B, Dobrowolski C, Rojas R, Karn J. Alvarez-Carbonell D, et al. Among authors: karn j. Retrovirology. 2017 Feb 6;14(1):9. doi: 10.1186/s12977-017-0335-8. Retrovirology. 2017. PMID: 28166799 Free PMC article.

10

The Glucocorticoid Receptor Is a Critical Regulator of HIV Latency in Human Microglial Cells.

Alvarez-Carbonell D, Ye F, Ramanath N, Dobrowolski C, Karn J. Alvarez-Carbonell D, et al. Among authors: karn j. J Neuroimmune Pharmacol. 2019 Mar;14(1):94-109. doi: 10.1007/s11481-018-9798-1. Epub 2018 Jul 10. J Neuroimmune Pharmacol. 2019. PMID: 29987742 Free PMC article.

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