Abdel-Aziz SA - Search Results

1

Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy.

Soltan OM, Shoman ME, Abdel-Aziz SA, Narumi A, Konno H, Abdel-Aziz M. Soltan OM, et al. Eur J Med Chem. 2021 Dec 5;225:113768. doi: 10.1016/j.ejmech.2021.113768. Epub 2021 Aug 14. Eur J Med Chem. 2021. PMID: 34450497 Review.

2

Design, synthesis and anticancer activity of new monastrol analogues bearing 1,3,4-oxadiazole moiety.

Ragab FAF, Abou-Seri SM, Abdel-Aziz SA, Alfayomy AM, Aboelmagd M. Ragab FAF, et al. Eur J Med Chem. 2017 Sep 29;138:140-151. doi: 10.1016/j.ejmech.2017.06.026. Epub 2017 Jun 15. Eur J Med Chem. 2017. PMID: 28667871

3

Design and synthesis of new 1,6-dihydropyrimidin-2-thio derivatives targeting VEGFR-2: Molecular docking and antiproliferative evaluation.

Marzouk AA, Abdel-Aziz SA, Abdelrahman KS, Wanas AS, Gouda AM, Youssif BGM, Abdel-Aziz M. Marzouk AA, et al. Bioorg Chem. 2020 Sep;102:104090. doi: 10.1016/j.bioorg.2020.104090. Epub 2020 Jul 10. Bioorg Chem. 2020. PMID: 32683176

4

Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies.

Alfayomy AM, Abdel-Aziz SA, Marzouk AA, Shaykoon MSA, Narumi A, Konno H, Abou-Seri SM, Ragab FAF. Alfayomy AM, et al. Bioorg Chem. 2021 Mar;108:104555. doi: 10.1016/j.bioorg.2020.104555. Epub 2020 Dec 15. Bioorg Chem. 2021. PMID: 33376011

5

JNK signaling as a target for anticancer therapy.

Abdelrahman KS, Hassan HA, Abdel-Aziz SA, Marzouk AA, Narumi A, Konno H, Abdel-Aziz M. Abdelrahman KS, et al. Pharmacol Rep. 2021 Apr;73(2):405-434. doi: 10.1007/s43440-021-00238-y. Epub 2021 Mar 12. Pharmacol Rep. 2021. PMID: 33710509 Review.

6

Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile.

Abdel-Aziz SA, Taher ES, Lan P, Asaad GF, Gomaa HAM, El-Koussi NA, Youssif BGM. Abdel-Aziz SA, et al. Bioorg Chem. 2021 Jun;111:104890. doi: 10.1016/j.bioorg.2021.104890. Epub 2021 Apr 8. Bioorg Chem. 2021. PMID: 33872924

7

Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.

Hofny HA, Mohamed MFA, Gomaa HAM, Abdel-Aziz SA, Youssif BGM, El-Koussi NA, Aboraia AS. Hofny HA, et al. Bioorg Chem. 2021 Jul;112:104920. doi: 10.1016/j.bioorg.2021.104920. Epub 2021 Apr 19. Bioorg Chem. 2021. PMID: 33910078

8

New pyrimidine/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX-2/sEH dual inhibition.

Abdel-Aziz SA, Taher ES, Lan P, El-Koussi NA, Salem OIA, Gomaa HAM, Youssif BGM. Abdel-Aziz SA, et al. Arch Pharm (Weinheim). 2022 Jul;355(7):e2200024. doi: 10.1002/ardp.202200024. Epub 2022 Apr 15. Arch Pharm (Weinheim). 2022. PMID: 35429006

9

Development and Assessment of 1,5-Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK-2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation.

Abdelrahman KS, Hassan HA, Abdel-Aziz SA, Marzouk AA, Shams R, Osawa K, Abdel-Aziz M, Konno H. Abdelrahman KS, et al. Among authors: abdel aziz sa. Molecules. 2023 Sep 8;28(18):6521. doi: 10.3390/molecules28186521. Molecules. 2023. PMID: 37764297 Free PMC article.

10

Development of 1,5-diarylpyrazoles as EGFR/JNK-2 dual inhibitors: design, synthesis, moleecular docking, and bioactivity evaluation.

Soltan OM, Abdel-Aziz SA, Sh Shaykoon M, Osawa K, Narumi A, Abdel-Aziz M, Shoman ME, Konno H. Soltan OM, et al. Among authors: abdel aziz sa. Bioorg Med Chem Lett. 2024 Apr 1;102:129673. doi: 10.1016/j.bmcl.2024.129673. Epub 2024 Feb 24. Bioorg Med Chem Lett. 2024. PMID: 38408511

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