Nam S - Search Results

1

Targeting the non-ATP-binding pocket of the MAP kinase p38γ mediates a novel mechanism of cytotoxicity in cutaneous T-cell lymphoma (CTCL).

Zhang XH, Chen CH, Li H, Hsiang J, Wu X, Hu W, Horne D, Nam S, Shively J, Rosen ST. Zhang XH, et al. Among authors: nam s. FEBS Lett. 2021 Oct;595(20):2570-2592. doi: 10.1002/1873-3468.14186. Epub 2021 Sep 15. FEBS Lett. 2021. PMID: 34455585 Free PMC article.

2

Synthesis and anticancer activities of ageladine A and structural analogs.

Ma Y, Nam S, Jove R, Yakushijin K, Horne DA. Ma Y, et al. Among authors: nam s. Bioorg Med Chem Lett. 2010 Jan 1;20(1):83-6. doi: 10.1016/j.bmcl.2009.11.036. Epub 2009 Nov 14. Bioorg Med Chem Lett. 2010. PMID: 19948404 Free PMC article.

3

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells.

Nam S, Xie J, Perkins A, Ma Y, Yang F, Wu J, Wang Y, Xu RZ, Huang W, Horne DA, Jove R. Nam S, et al. Mol Oncol. 2012 Oct;6(5):484-93. doi: 10.1016/j.molonc.2012.05.002. Epub 2012 Jun 2. Mol Oncol. 2012. PMID: 22717603 Free PMC article.

4

Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.

Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, Liang W, Yang F, Ma Y, Horne D, Jove R. Tian Y, et al. Among authors: nam s. PLoS One. 2012;7(11):e49306. doi: 10.1371/journal.pone.0049306. Epub 2012 Nov 16. PLoS One. 2012. PMID: 23166634 Free PMC article.

5

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.

Nam S, Wen W, Schroeder A, Herrmann A, Yu H, Cheng X, Merz KH, Eisenbrand G, Li H, Yuan YC, Jove R. Nam S, et al. Mol Oncol. 2013 Jun;7(3):369-78. doi: 10.1016/j.molonc.2012.10.013. Epub 2012 Nov 16. Mol Oncol. 2013. PMID: 23206899 Free PMC article.

6

A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling.

Yang F, Nam S, Zhao R, Tian Y, Liu L, Horne DA, Jove R. Yang F, et al. Among authors: nam s. Cancer Biol Ther. 2013 Nov;14(11):1024-31. doi: 10.4161/cbt.26045. Epub 2013 Aug 28. Cancer Biol Ther. 2013. PMID: 24025361 Free PMC article.

7

A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling.

Yang F, Nam S, Brown CE, Zhao R, Starr R, Ma Y, Xie J, Horne DA, Malkas LH, Jove R, Hickey RJ. Yang F, et al. Among authors: nam s. PLoS One. 2014 Apr 14;9(4):e94443. doi: 10.1371/journal.pone.0094443. eCollection 2014. PLoS One. 2014. PMID: 24732116 Free PMC article.

8

Enantioselective synthesis of α-secondary and α-tertiary piperazin-2-ones and piperazines by catalytic asymmetric allylic alkylation.

Korch KM, Eidamshaus C, Behenna DC, Nam S, Horne D, Stoltz BM. Korch KM, et al. Among authors: nam s. Angew Chem Int Ed Engl. 2015 Jan 2;54(1):179-83. doi: 10.1002/anie.201408609. Epub 2014 Nov 7. Angew Chem Int Ed Engl. 2015. PMID: 25382664 Free PMC article.

9

Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity.

Baumann M, Dieskau AP, Loertscher BM, Walton MC, Nam S, Xie J, Horne D, Overman LE. Baumann M, et al. Among authors: nam s. Chem Sci. 2015;6(8):4451-4457. doi: 10.1039/C5SC01536G. Chem Sci. 2015. PMID: 26301062 Free PMC article.

10

Site-Selective Aliphatic C-H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide.

Quinn RK, Könst ZA, Michalak SE, Schmidt Y, Szklarski AR, Flores AR, Nam S, Horne DA, Vanderwal CD, Alexanian EJ. Quinn RK, et al. Among authors: nam s. J Am Chem Soc. 2016 Jan 20;138(2):696-702. doi: 10.1021/jacs.5b12308. Epub 2016 Jan 6. J Am Chem Soc. 2016. PMID: 26694767 Free PMC article.

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