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DAMPening COVID-19 Severity by Attenuating Danger Signals.
Silva-Lagos LA, Pillay J, van Meurs M, Smink A, van der Voort PHJ, de Vos P. Silva-Lagos LA, et al. Front Immunol. 2021 Aug 12;12:720192. doi: 10.3389/fimmu.2021.720192. eCollection 2021. Front Immunol. 2021. PMID: 34456928 Free PMC article. Review.
Inclusion of extracellular matrix molecules and necrostatin-1 in the intracapsular environment of alginate-based microcapsules synergistically protects pancreatic β cells against cytokine-induced inflammatory stress.
Qin T, Hu S, Smink AM, de Haan BJ, Silva-Lagos LA, Lakey JRT, de Vos P. Qin T, et al. Among authors: silva lagos la. Acta Biomater. 2022 Jul 1;146:434-449. doi: 10.1016/j.actbio.2022.04.042. Epub 2022 Apr 30. Acta Biomater. 2022. PMID: 35500812 Free article.
β(2 → 1)-β(2 → 6) branched graminan-type fructans and β(2 → 1) linear fructans impact mucus-related and endoplasmic reticulum stress-related genes in goblet cells and attenuate inflammatory responses in a fructan dependent fashion.
Fernández-Lainez C, Aan de Stegge M, Silva-Lagos LA, López-Velázquez G, de Vos P. Fernández-Lainez C, et al. Among authors: silva lagos la. Food Funct. 2023 Feb 6;14(3):1338-1348. doi: 10.1039/d2fo02710k. Food Funct. 2023. PMID: 36656019
β(2 → 1)-β(2 → 6) and β(2 → 1) fructans protect from impairment of intestinal tight junction's gene expression and attenuate human dendritic cell responses in a fructan-dependent fashion.
Fernández-Lainez C, Aan de Stegge M, Silva-Lagos LA, López-Velázquez G, de Vos P. Fernández-Lainez C, et al. Among authors: silva lagos la. Carbohydr Polym. 2023 Nov 15;320:121259. doi: 10.1016/j.carbpol.2023.121259. Epub 2023 Aug 3. Carbohydr Polym. 2023. PMID: 37659831 Free article.