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Page 1
A Chemical Toolbox for Labeling and Degrading Engineered Cas Proteins.
Gama-Brambila RA, Chen J, Dabiri Y, Tascher G, Němec V, Münch C, Song G, Knapp S, Cheng X. Gama-Brambila RA, et al. Among authors: knapp s. JACS Au. 2021 May 12;1(6):777-785. doi: 10.1021/jacsau.1c00007. eCollection 2021 Jun 28. JACS Au. 2021. PMID: 34467332 Free PMC article.
Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
Němec V, Hylsová M, Maier L, Flegel J, Sievers S, Ziegler S, Schröder M, Berger BT, Chaikuad A, Valčíková B, Uldrijan S, Drápela S, Souček K, Waldmann H, Knapp S, Paruch K. Němec V, et al. Among authors: knapp s. Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1062-1066. doi: 10.1002/anie.201810312. Epub 2018 Dec 20. Angew Chem Int Ed Engl. 2019. PMID: 30569600
A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins.
Schwalm MP, Berger LM, Meuter MN, Vasta JD, Corona CR, Röhm S, Berger BT, Farges F, Beinert SM, Preuss F, Morasch V, Rogov VV, Mathea S, Saxena K, Robers MB, Müller S, Knapp S. Schwalm MP, et al. Among authors: knapp s. Front Cell Dev Biol. 2022 May 26;10:886537. doi: 10.3389/fcell.2022.886537. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35721509 Free PMC article.
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2.
Němec V, Remeš M, Beňovský P, Böck MC, Šranková E, Wong JF, Cros J, Williams E, Tse LH, Smil D, Ensan D, Isaac MB, Al-Awar R, Gomolková R, Ursachi VC, Fafílek B, Kahounová Z, Víchová R, Vacek O, Berger BT, Wells CI, Corona CR, Vasta JD, Robers MB, Krejci P, Souček K, Bullock AN, Knapp S, Paruch K. Němec V, et al. Among authors: knapp s. J Med Chem. 2024 Aug 8;67(15):12632-12659. doi: 10.1021/acs.jmedchem.4c00629. Epub 2024 Jul 18. J Med Chem. 2024. PMID: 39023313 Free PMC article.
Chem-CRISPR/dCas9FCPF: a platform for chemically induced epigenome editing.
Altinbay M, Wang J, Chen J, Schäfer D, Sprang M, Blagojevic B, Wölfl S, Andrade-Navarro MA, Dikic I, Knapp S, Cheng X. Altinbay M, et al. Among authors: knapp s. Nucleic Acids Res. 2024 Oct 28;52(19):11587-11601. doi: 10.1093/nar/gkae798. Nucleic Acids Res. 2024. PMID: 39315698 Free PMC article.
Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε.
Haag A, Němec V, Janovská P, Bartošíková J, Adhikari B, Müller J, Schwalm MP, Čada Š, Ohmayer U, Daub H, Kim Y, Born F, Wolf E, Bryja V, Knapp S. Haag A, et al. Among authors: knapp s. J Med Chem. 2024 Dec 27. doi: 10.1021/acs.jmedchem.4c02201. Online ahead of print. J Med Chem. 2024. PMID: 39729064
A chemical toolbox for the study of bromodomains and epigenetic signaling.
Wu Q, Heidenreich D, Zhou S, Ackloo S, Krämer A, Nakka K, Lima-Fernandes E, Deblois G, Duan S, Vellanki RN, Li F, Vedadi M, Dilworth J, Lupien M, Brennan PE, Arrowsmith CH, Müller S, Fedorov O, Filippakopoulos P, Knapp S. Wu Q, et al. Among authors: knapp s. Nat Commun. 2019 Apr 23;10(1):1915. doi: 10.1038/s41467-019-09672-2. Nat Commun. 2019. PMID: 31015424 Free PMC article.
1,328 results