Leonard WJ - Search Results

1

Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells.

Lisco A, Hsu AP, Dimitrova D, Proctor DM, Mace EM, Ye P, Anderson MV, Hicks SN, Grivas C, Hammoud DA, Manion M, Starrett GJ, Farrel A, Dobbs K, Brownell I, Buck C, Notarangelo LD, Orange JS, Leonard WJ, Orestes MI, Peters AT, Kanakry JA, Segre JA, Kong HH, Sereti I. Lisco A, et al. Among authors: leonard wj. N Engl J Med. 2021 Sep 2;385(10):921-929. doi: 10.1056/NEJMoa2102715. N Engl J Med. 2021. PMID: 34469647 Free PMC article.

2

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity.

Imada K, Bloom ET, Nakajima H, Horvath-Arcidiacono JA, Udy GB, Davey HW, Leonard WJ. Imada K, et al. Among authors: leonard wj. J Exp Med. 1998 Dec 7;188(11):2067-74. doi: 10.1084/jem.188.11.2067. J Exp Med. 1998. PMID: 9841920 Free PMC article.

3

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium.

Kobayashi T, Voisin B, Kim DY, Kennedy EA, Jo JH, Shih HY, Truong A, Doebel T, Sakamoto K, Cui CY, Schlessinger D, Moro K, Nakae S, Horiuchi K, Zhu J, Leonard WJ, Kong HH, Nagao K. Kobayashi T, et al. Among authors: leonard wj. Cell. 2019 Feb 21;176(5):982-997.e16. doi: 10.1016/j.cell.2018.12.031. Epub 2019 Jan 31. Cell. 2019. PMID: 30712873 Free PMC article.

4

Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.

Puel A, Ziegler SF, Buckley RH, Leonard WJ. Puel A, et al. Among authors: leonard wj. Nat Genet. 1998 Dec;20(4):394-7. doi: 10.1038/3877. Nat Genet. 1998. PMID: 9843216

5

Mutations in the gene for the IL-7 receptor result in T(-)B(+)NK(+) severe combined immunodeficiency disease.

Puel A, Leonard WJ. Puel A, et al. Among authors: leonard wj. Curr Opin Immunol. 2000 Aug;12(4):468-73. doi: 10.1016/s0952-7915(00)00122-9. Curr Opin Immunol. 2000. PMID: 10899029 Review.

6

In vivo antitumor activity of interleukin 21 mediated by natural killer cells.

Wang G, Tschoi M, Spolski R, Lou Y, Ozaki K, Feng C, Kim G, Leonard WJ, Hwu P. Wang G, et al. Among authors: leonard wj. Cancer Res. 2003 Dec 15;63(24):9016-22. Cancer Res. 2003. PMID: 14695220

7

Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways.

Kovanen PE, Leonard WJ. Kovanen PE, et al. Among authors: leonard wj. Immunol Rev. 2004 Dec;202:67-83. doi: 10.1111/j.0105-2896.2004.00203.x. Immunol Rev. 2004. PMID: 15546386 Review.

8

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

Zeng R, Spolski R, Finkelstein SE, Oh S, Kovanen PE, Hinrichs CS, Pise-Masison CA, Radonovich MF, Brady JN, Restifo NP, Berzofsky JA, Leonard WJ. Zeng R, et al. Among authors: leonard wj. J Exp Med. 2005 Jan 3;201(1):139-48. doi: 10.1084/jem.20041057. J Exp Med. 2005. PMID: 15630141 Free PMC article.

9

IL-21 is an immune activator that also mediates suppression via IL-10.

Spolski R, Leonard WJ. Spolski R, et al. Among authors: leonard wj. Crit Rev Immunol. 2010;30(6):559-70. doi: 10.1615/critrevimmunol.v30.i6.50. Crit Rev Immunol. 2010. PMID: 21175418 Review.

10

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells.

Lin JX, Du N, Li P, Kazemian M, Gebregiorgis T, Spolski R, Leonard WJ. Lin JX, et al. Among authors: leonard wj. Nat Commun. 2017 Nov 6;8(1):1320. doi: 10.1038/s41467-017-01477-5. Nat Commun. 2017. PMID: 29105654 Free PMC article.

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