Wang S - Search Results

1

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.

Xiang W, Zhao L, Han X, Qin C, Miao B, McEachern D, Wang Y, Metwally H, Kirchhoff PD, Wang L, Matvekas A, He M, Wen B, Sun D, Wang S. Xiang W, et al. Among authors: wang l, wang y, wang s. J Med Chem. 2021 Sep 23;64(18):13487-13509. doi: 10.1021/acs.jmedchem.1c00900. Epub 2021 Sep 2. J Med Chem. 2021. PMID: 34473519 Free PMC article.

2

Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.

Enyedy IJ, Wang J, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang j, wang s. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1775-8. doi: 10.1016/s0960-894x(02)00243-3. Bioorg Med Chem Lett. 2002. PMID: 12067559

3

Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors.

Enyedy IJ, Sakamuri S, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang s. Bioorg Med Chem Lett. 2003 Feb 10;13(3):513-7. doi: 10.1016/s0960-894x(02)00943-5. Bioorg Med Chem Lett. 2003. PMID: 12565962

4

Comparative evaluation of 11 scoring functions for molecular docking.

Wang R, Lu Y, Wang S. Wang R, et al. Among authors: wang s. J Med Chem. 2003 Jun 5;46(12):2287-303. doi: 10.1021/jm0203783. J Med Chem. 2003. PMID: 12773034

5

Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.

Varady J, Wu X, Fang X, Min J, Hu Z, Levant B, Wang S. Varady J, et al. Among authors: wang s. J Med Chem. 2003 Oct 9;46(21):4377-92. doi: 10.1021/jm030085p. J Med Chem. 2003. PMID: 14521403

6

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S. Nikolovska-Coleska Z, et al. Among authors: wang s, wang r. J Med Chem. 2004 May 6;47(10):2430-40. doi: 10.1021/jm030420+. J Med Chem. 2004. PMID: 15115387

7

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S. Sun H, et al. Among authors: wang s. J Med Chem. 2004 Aug 12;47(17):4147-50. doi: 10.1021/jm0499108. J Med Chem. 2004. PMID: 15293984

8

Design, synthesis, and evaluation of hexahydrobenz[f]isoquinolines as a novel class of dopamine 3 receptor ligands.

Wu X, Chen J, Ji M, Varady J, Levant B, Wang S. Wu X, et al. Among authors: wang s. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5813-6. doi: 10.1016/j.bmcl.2004.09.047. Bioorg Med Chem Lett. 2004. PMID: 15501046

9

Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.

Sun H, Nikolovska-Coleska Z, Chen J, Yang CY, Tomita Y, Pan H, Yoshioka Y, Krajewski K, Roller PP, Wang S. Sun H, et al. Among authors: wang s. Bioorg Med Chem Lett. 2005 Feb 1;15(3):793-7. doi: 10.1016/j.bmcl.2004.11.008. Bioorg Med Chem Lett. 2005. PMID: 15664859

10

CHMIS-C: a comprehensive herbal medicine information system for cancer.

Fang X, Shao L, Zhang H, Wang S. Fang X, et al. Among authors: wang s. J Med Chem. 2005 Mar 10;48(5):1481-8. doi: 10.1021/jm049838d. J Med Chem. 2005. PMID: 15743190

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