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Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons.
Cheng YC, Snavely A, Barrett LB, Zhang X, Herman C, Frost DJ, Riva P, Tochitsky I, Kawaguchi R, Singh B, Ivanis J, Huebner EA, Arvanites A, Oza V, Davidow L, Maeda R, Sakuma M, Grantham A, Wang Q, Chang AN, Pfaff K, Costigan M, Coppola G, Rubin LL, Schwer B, Alt FW, Woolf CJ. Cheng YC, et al. Among authors: frost dj. Cell Rep. 2021 Sep 7;36(10):109666. doi: 10.1016/j.celrep.2021.109666. Cell Rep. 2021. PMID: 34496254 Free PMC article.
Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation.
Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, Woolf CJ. Huang X, et al. Cell Rep. 2021 Jun 8;35(10):109224. doi: 10.1016/j.celrep.2021.109224. Cell Rep. 2021. PMID: 34107252 Free PMC article.
Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis.
Huang X, Lee S, Chen K, Kawaguchi R, Wiskow O, Ghosh S, Frost D, Perrault L, Pandey R, Klim JR, Boivin B, Hermawan C, Livak KJ, Geschwind DH, Wainger BJ, Eggan KC, Bean BP, Woolf CJ. Huang X, et al. Brain Commun. 2024 Jun 11;6(3):fcae202. doi: 10.1093/braincomms/fcae202. eCollection 2024. Brain Commun. 2024. PMID: 38911266 Free PMC article.
Fitness trade-offs of multidrug efflux pumps in Escherichia coli K-12 in acid or base, and with aromatic phytochemicals.
Liu Y, Van Horn AM, Pham MTN, Dinh BNN, Chen R, Raphael SDR, Paulino A, Thaker K, Somadder A, Frost DJ, Menke CC, Slimak ZC, Slonczewski JL. Liu Y, et al. Among authors: frost dj. Appl Environ Microbiol. 2024 Feb 21;90(2):e0209623. doi: 10.1128/aem.02096-23. Epub 2024 Jan 30. Appl Environ Microbiol. 2024. PMID: 38289137 Free PMC article.
Co-clinical Modeling of the Activity of the BET Inhibitor Mivebresib (ABBV-075) in AML.
Albert DH, Goodwin NC, Davies AM, Rowe J, Feuer G, Boyiadzis M, Dorritie KA, Mancini M, Gandour-Edwards R, Jonas BA, Borthakur G, Aldoss I, Rizzieri DA, Odenike O, Prebet T, Singh S, Popovic R, Shen YU, McDaniel KF, Kati WM, Modi DA, Motwani M, Wolff JE, Frost DJ. Albert DH, et al. Among authors: frost dj. In Vivo. 2022 Jul-Aug;36(4):1615-1627. doi: 10.21873/invivo.12872. In Vivo. 2022. PMID: 35738590 Free PMC article.
Reduced methane-bearing fluids as a source for diamond.
Matjuschkin V, Woodland AB, Frost DJ, Yaxley GM. Matjuschkin V, et al. Among authors: frost dj. Sci Rep. 2020 Apr 24;10(1):6961. doi: 10.1038/s41598-020-63518-2. Sci Rep. 2020. PMID: 32332772 Free PMC article.
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