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A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: a potential drug target in IPF.
Schuliga M, Kanwal A, Read J, Blokland KEC, Burgess JK, Prêle CM, Mutsaers SE, Grainge C, Thomson C, James A, Bartlett NW, Knight DA. Schuliga M, et al. Among authors: blokland kec. Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L859-L871. doi: 10.1152/ajplung.00574.2020. Epub 2021 Sep 15. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34524912 Free article.
Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis.
Waters DW, Blokland KEC, Pathinayake PS, Burgess JK, Mutsaers SE, Prele CM, Schuliga M, Grainge CL, Knight DA. Waters DW, et al. Among authors: blokland kec. Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L162-L172. doi: 10.1152/ajplung.00037.2018. Epub 2018 Apr 26. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29696986 Free PMC article. Review.
Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.
Schuliga M, Pechkovsky DV, Read J, Waters DW, Blokland KEC, Reid AT, Hogaboam CM, Khalil N, Burgess JK, Prêle CM, Mutsaers SE, Jaffar J, Westall G, Grainge C, Knight DA. Schuliga M, et al. Among authors: blokland kec. J Cell Mol Med. 2018 Dec;22(12):5847-5861. doi: 10.1111/jcmm.13855. Epub 2018 Sep 26. J Cell Mol Med. 2018. PMID: 30255990 Free PMC article.
STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts.
Waters DW, Blokland KEC, Pathinayake PS, Wei L, Schuliga M, Jaffar J, Westall GP, Hansbro PM, Prele CM, Mutsaers SE, Bartlett NW, Burgess JK, Grainge CL, Knight DA. Waters DW, et al. Among authors: blokland kec. Am J Respir Cell Mol Biol. 2019 Jul;61(1):61-73. doi: 10.1165/rcmb.2018-0328OC. Am J Respir Cell Mol Biol. 2019. PMID: 30608861
Extracellular vesicles in lung health, disease, and therapy.
McVey MJ, Maishan M, Blokland KEC, Bartlett N, Kuebler WM. McVey MJ, et al. Among authors: blokland kec. Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L977-L989. doi: 10.1152/ajplung.00546.2018. Epub 2019 Mar 20. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30892076 Free article. Review.
Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner.
Schuliga M, Read J, Blokland KEC, Waters DW, Burgess J, Prêle C, Mutsaers SE, Jaffar J, Westall G, Reid A, James A, Grainge C, Knight DA. Schuliga M, et al. Among authors: blokland kec. Clin Sci (Lond). 2020 Apr 17;134(7):889-905. doi: 10.1042/CS20191160. Clin Sci (Lond). 2020. PMID: 32219338
A Senescence Bystander Effect in Human Lung Fibroblasts.
Waters DW, Schuliga M, Pathinayake PS, Wei L, Tan HY, Blokland KEC, Jaffar J, Westall GP, Burgess JK, Prêle CM, Mutsaers SE, Grainge CL, Knight DA. Waters DW, et al. Among authors: blokland kec. Biomedicines. 2021 Sep 4;9(9):1162. doi: 10.3390/biomedicines9091162. Biomedicines. 2021. PMID: 34572347 Free PMC article.
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