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Page 1
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis.
Szabó V, Csákány-Papp N, Görög M, Madácsy T, Varga Á, Kiss A, Tél B, Jójárt B, Crul T, Dudás K, Bagyánszki M, Bódi N, Ayaydin F, Jee S, Tiszlavicz L, Stauderman KA, Hebbar S, Pallagi P, Maléth J. Szabó V, et al. Among authors: pallagi p. JCI Insight. 2023 Jul 10;8(13):e167645. doi: 10.1172/jci.insight.167645. JCI Insight. 2023. PMID: 37227782 Free PMC article.
Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl⁻ channels and luminal anion exchangers.
Pallagi P, Venglovecz V, Rakonczay Z Jr, Borka K, Korompay A, Ozsvári B, Judák L, Sahin-Tóth M, Geisz A, Schnúr A, Maléth J, Takács T, Gray MA, Argent BE, Mayerle J, Lerch MM, Wittmann T, Hegyi P. Pallagi P, et al. Gastroenterology. 2011 Dec;141(6):2228-2239.e6. doi: 10.1053/j.gastro.2011.08.039. Epub 2011 Sep 3. Gastroenterology. 2011. PMID: 21893120 Free PMC article.
The role of pancreatic ductal secretion in protection against acute pancreatitis in mice*.
Pallagi P, Balla Z, Singh AK, Dósa S, Iványi B, Kukor Z, Tóth A, Riederer B, Liu Y, Engelhardt R, Jármay K, Szabó A, Janovszky A, Perides G, Venglovecz V, Maléth J, Wittmann T, Takács T, Gray MA, Gácser A, Hegyi P, Seidler U, Rakonczay Z Jr. Pallagi P, et al. Crit Care Med. 2014 Mar;42(3):e177-88. doi: 10.1097/CCM.0000000000000101. Crit Care Med. 2014. PMID: 24368347
Pancreatitis severity in mice with impaired CFTR function but pancreatic sufficiency is mediated via ductal and inflammatory cells-Not acinar cells.
Trapp S, Aghdassi AA, Glaubitz J, Sendler M, Weiss FU, Kühn JP, Kromrey ML, Mahajan UM, Pallagi P, Rakonczay Z Jr, Venglovecz V, Lerch MM, Hegyi P, Mayerle J. Trapp S, et al. Among authors: pallagi p. J Cell Mol Med. 2021 May;25(10):4658-4670. doi: 10.1111/jcmm.16404. Epub 2021 Mar 8. J Cell Mol Med. 2021. PMID: 33682322 Free PMC article.
Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis.
Maléth J, Balázs A, Pallagi P, Balla Z, Kui B, Katona M, Judák L, Németh I, Kemény LV, Rakonczay Z Jr, Venglovecz V, Földesi I, Pető Z, Somorácz Á, Borka K, Perdomo D, Lukacs GL, Gray MA, Monterisi S, Zaccolo M, Sendler M, Mayerle J, Kühn JP, Lerch MM, Sahin-Tóth M, Hegyi P. Maléth J, et al. Among authors: pallagi p. Gastroenterology. 2015 Feb;148(2):427-39.e16. doi: 10.1053/j.gastro.2014.11.002. Epub 2014 Nov 7. Gastroenterology. 2015. PMID: 25447846 Free PMC article.
Impaired regulation of PMCA activity by defective CFTR expression promotes epithelial cell damage in alcoholic pancreatitis and hepatitis.
Madácsy T, Varga Á, Papp N, Tél B, Pallagi P, Szabó V, Kiss A, Fanczal J, Rakonczay Z Jr, Tiszlavicz L, Rázga Z, Hohwieler M, Kleger A, Gray M, Hegyi P, Maléth J. Madácsy T, et al. Among authors: pallagi p. Cell Mol Life Sci. 2022 Apr 28;79(5):265. doi: 10.1007/s00018-022-04287-1. Cell Mol Life Sci. 2022. PMID: 35484438 Free PMC article.
32 results