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Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation.
Dolmatova EV, Forrester SJ, Wang K, Ou Z, Williams HC, Joseph G, Kumar S, Valdivia A, Kowalczyk AP, Qu H, Jo H, Lassègue B, Hernandes MS, Griendling KK. Dolmatova EV, et al. Among authors: williams hc. Cardiovasc Res. 2022 Aug 24;118(11):2506-2518. doi: 10.1093/cvr/cvab295. Cardiovasc Res. 2022. PMID: 34528082 Free PMC article.
Transforming growth factor β inhibits platelet derived growth factor-induced vascular smooth muscle cell proliferation via Akt-independent, Smad-mediated cyclin D1 downregulation.
Martin-Garrido A, Williams HC, Lee M, Seidel-Rogol B, Ci X, Dong JT, Lassègue B, Martín AS, Griendling KK. Martin-Garrido A, et al. Among authors: williams hc. PLoS One. 2013 Nov 13;8(11):e79657. doi: 10.1371/journal.pone.0079657. eCollection 2013. PLoS One. 2013. PMID: 24236150 Free PMC article.
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.
Paredes F, Sheldon K, Lassègue B, Williams HC, Faidley EA, Benavides GA, Torres G, Sanhueza-Olivares F, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A. Paredes F, et al. Among authors: williams hc. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1789-1794. doi: 10.1073/pnas.1720693115. Epub 2018 Feb 6. Proc Natl Acad Sci U S A. 2018. PMID: 29434038 Free PMC article.
Reply to Bailey et al.: New perspectives on the novel role of the Poldip2/ACSM1 axis in a functional mammalian lipoylation salvage pathway.
Paredes F, Lassègue B, Williams HC, Faidley EA, Benavides GA, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A. Paredes F, et al. Among authors: williams hc. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7460-E7461. doi: 10.1073/pnas.1807968115. Epub 2018 Jul 24. Proc Natl Acad Sci U S A. 2018. PMID: 30042216 Free PMC article. No abstract available.
Mitochondrial Protein Poldip2 (Polymerase Delta Interacting Protein 2) Controls Vascular Smooth Muscle Differentiated Phenotype by O-Linked GlcNAc (N-Acetylglucosamine) Transferase-Dependent Inhibition of a Ubiquitin Proteasome System.
Paredes F, Williams HC, Quintana RA, San Martin A. Paredes F, et al. Among authors: williams hc. Circ Res. 2020 Jan 3;126(1):41-56. doi: 10.1161/CIRCRESAHA.119.315932. Epub 2019 Oct 28. Circ Res. 2020. PMID: 31656131 Free PMC article.
568 results