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Evaluation of the Safety, Tolerability, and Pharmacokinetic Profiles of TP0473292 (TS-161), A Prodrug of a Novel Orthosteric mGlu2/3 Receptor Antagonist TP0178894, in Healthy Subjects and Its Antidepressant-Like Effects in Rodents.
Watanabe M, Marcy B, Hiroki A, Watase H, Kinoshita K, Iijima M, Marumo T, Zarate CA, Chaki S. Watanabe M, et al. Among authors: watase h. Int J Neuropsychopharmacol. 2022 Feb 11;25(2):106-117. doi: 10.1093/ijnp/pyab062. Int J Neuropsychopharmacol. 2022. PMID: 34534292 Free PMC article. Clinical Trial.
Novel Compound Induces Erythropoietin Secretion through Liver Effects in Chronic Kidney Disease Patients and Healthy Volunteers.
Shinfuku A, Shimazaki T, Fujiwara M, Sato F, Watase H, Numazaki T, Kawakita Y, Mutoh M, Yamasaki H, Takayama N, Kato S, Sugimoto T, Maruyama J. Shinfuku A, et al. Among authors: watase h. Am J Nephrol. 2018;48(3):157-164. doi: 10.1159/000492181. Epub 2018 Sep 3. Am J Nephrol. 2018. PMID: 30176654 Free PMC article. Clinical Trial.
Impact of Reduced Renal Function on the Glucose-Lowering Effects of Luseogliflozin, a Selective SGLT2 Inhibitor, Assessed by Continuous Glucose Monitoring in Japanese Patients with Type 2 Diabetes Mellitus.
Jinnouchi H, Nozaki K, Watase H, Omiya H, Sakai S, Samukawa Y. Jinnouchi H, et al. Among authors: watase h. Adv Ther. 2016 Mar;33(3):460-79. doi: 10.1007/s12325-016-0291-z. Epub 2016 Feb 5. Adv Ther. 2016. PMID: 26846284 Free PMC article. Clinical Trial.
Application of model-informed drug development (MIDD) for dose selection in regulatory submissions for drug approval in Japan.
JPMA MIDD Task force; Sasaki T, Katsube T, Hayato S, Yamaguchi S, Tanaka J, Yoshimatsu H, Nakanishi Y, Kitamura A, Watase H, Suganami H, Matsuoka N, Hasegawa C. JPMA MIDD Task force, et al. Among authors: watase h. J Pharmacokinet Pharmacodyn. 2025 Jan 6;52(1):10. doi: 10.1007/s10928-024-09954-3. J Pharmacokinet Pharmacodyn. 2025. PMID: 39762622
Corrigendum: Association of airway obstruction with first-pass success and intubation-related adverse events in the emergency department: multicenter prospective observational studies.
Takahashi J, Goto T, Fujitani S, Okamoto H, Hagiwara Y, Watase H, Hasegawa K; Japanese Emergency Medicine Network Investigators. Takahashi J, et al. Among authors: watase h. Front Med (Lausanne). 2023 Oct 20;10:1307868. doi: 10.3389/fmed.2023.1307868. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37928480 Free PMC article.
Association of airway obstruction with first-pass success and intubation-related adverse events in the emergency department: multicenter prospective observational studies.
Takahashi J, Goto T, Fujitani S, Okamoto H, Hagiwara Y, Watase H, Hasegawa K; Japanese Emergency Medicine Network Investigators. Takahashi J, et al. Among authors: watase h. Front Med (Lausanne). 2023 May 25;10:1199750. doi: 10.3389/fmed.2023.1199750. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37305119 Free PMC article.
99 results