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Choroid plexus APP regulates adult brain proliferation and animal behavior.
Arnaud K, Oliveira Moreira V, Vincent J, Dallerac G, Dubreuil C, Dupont E, Richter M, Müller UC, Rondi-Reig L, Prochiantz A, Di Nardo AA. Arnaud K, et al. Among authors: muller uc. Life Sci Alliance. 2021 Sep 20;4(11):e202000703. doi: 10.26508/lsa.202000703. Print 2021 Nov. Life Sci Alliance. 2021. PMID: 34544751 Free PMC article.
The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.
Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, Herms J, Buchholz C, Eckman CB, Korte M, Wolfer DP, Müller UC. Ring S, et al. Among authors: muller uc. J Neurosci. 2007 Jul 18;27(29):7817-26. doi: 10.1523/JNEUROSCI.1026-07.2007. J Neurosci. 2007. PMID: 17634375 Free PMC article.
APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP.
Weyer SW, Klevanski M, Delekate A, Voikar V, Aydin D, Hick M, Filippov M, Drost N, Schaller KL, Saar M, Vogt MA, Gass P, Samanta A, Jäschke A, Korte M, Wolfer DP, Caldwell JH, Müller UC. Weyer SW, et al. Among authors: muller uc. EMBO J. 2011 Jun 1;30(11):2266-80. doi: 10.1038/emboj.2011.119. Epub 2011 Apr 26. EMBO J. 2011. PMID: 21522131 Free PMC article.
Physiological functions of APP family proteins.
Müller UC, Zheng H. Müller UC, et al. Cold Spring Harb Perspect Med. 2012 Feb;2(2):a006288. doi: 10.1101/cshperspect.a006288. Cold Spring Harb Perspect Med. 2012. PMID: 22355794 Free PMC article. Review.
Hippocampal network oscillations in APP/APLP2-deficient mice.
Zhang X, Herrmann U, Weyer SW, Both M, Müller UC, Korte M, Draguhn A. Zhang X, et al. Among authors: muller uc. PLoS One. 2013 Apr 9;8(4):e61198. doi: 10.1371/journal.pone.0061198. Print 2013. PLoS One. 2013. PMID: 23585881 Free PMC article.
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, Müller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. Willem M, et al. Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864. Epub 2015 Aug 31. Nature. 2015. PMID: 26322584 Free PMC article.
117 results