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Roadmap for the use of base editors to decipher drug mechanism of action.
Aparicio-Prat E, Yan D, Mariotti M, Bassik M, Hess G, Fortin JP, Weston A, Xi HS, Stanton R. Aparicio-Prat E, et al. Among authors: fortin jp. PLoS One. 2021 Sep 21;16(9):e0257537. doi: 10.1371/journal.pone.0257537. eCollection 2021. PLoS One. 2021. PMID: 34547052 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35555261
A two-step strategy to enhance activity of low potency peptides.
Doyle JR, Harwood BN, Krishnaji ST, Krishnamurthy VM, Lin WE, Fortin JP, Kumar K, Kopin AS. Doyle JR, et al. Among authors: fortin jp. PLoS One. 2014 Nov 12;9(11):e110502. doi: 10.1371/journal.pone.0110502. eCollection 2014. PLoS One. 2014. PMID: 25391026 Free PMC article.
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet C, Mancini A, Breton B, Le Gouill C, Hauser AS, Normand C, Kobayashi H, Gross F, Hogue M, Lukasheva V, St-Onge S, Carrier M, Héroux M, Morissette S, Fauman EB, Fortin JP, Schann S, Leroy X, Gloriam DE, Bouvier M. Avet C, et al. Among authors: fortin jp. Elife. 2022 Mar 18;11:e74101. doi: 10.7554/eLife.74101. Elife. 2022. PMID: 35302493 Free PMC article.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
Griffith DA, Edmonds DJ, Fortin JP, Kalgutkar AS, Kuzmiski JB, Loria PM, Saxena AR, Bagley SW, Buckeridge C, Curto JM, Derksen DR, Dias JM, Griffor MC, Han S, Jackson VM, Landis MS, Lettiere D, Limberakis C, Liu Y, Mathiowetz AM, Patel JC, Piotrowski DW, Price DA, Ruggeri RB, Tess DA. Griffith DA, et al. Among authors: fortin jp. J Med Chem. 2022 Jun 23;65(12):8208-8226. doi: 10.1021/acs.jmedchem.1c01856. Epub 2022 Jun 1. J Med Chem. 2022. PMID: 35647711 Free PMC article.
134 results