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The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.
McDade E, Voytyuk I, Aisen P, Bateman RJ, Carrillo MC, De Strooper B, Haass C, Reiman EM, Sperling R, Tariot PN, Yan R, Masters CL, Vassar R, Lichtenthaler SF. McDade E, et al. Among authors: yan r. Nat Rev Neurol. 2021 Nov;17(11):703-714. doi: 10.1038/s41582-021-00545-1. Epub 2021 Sep 21. Nat Rev Neurol. 2021. PMID: 34548654 Review.
The β-Secretase BACE1 in Alzheimer's Disease.
Hampel H, Vassar R, De Strooper B, Hardy J, Willem M, Singh N, Zhou J, Yan R, Vanmechelen E, De Vos A, Nisticò R, Corbo M, Imbimbo BP, Streffer J, Voytyuk I, Timmers M, Tahami Monfared AA, Irizarry M, Albala B, Koyama A, Watanabe N, Kimura T, Yarenis L, Lista S, Kramer L, Vergallo A. Hampel H, et al. Among authors: yan r. Biol Psychiatry. 2021 Apr 15;89(8):745-756. doi: 10.1016/j.biopsych.2020.02.001. Epub 2020 Feb 13. Biol Psychiatry. 2021. PMID: 32223911 Free PMC article. Review.
β-Secretase1 biological markers for Alzheimer's disease: state-of-art of validation and qualification.
Hampel H, Lista S, Vanmechelen E, Zetterberg H, Giorgi FS, Galgani A, Blennow K, Caraci F, Das B, Yan R, Vergallo A; Alzheimer’s Precision Medicine Initiative (APMI). Hampel H, et al. Among authors: yan r. Alzheimers Res Ther. 2020 Oct 16;12(1):130. doi: 10.1186/s13195-020-00686-3. Alzheimers Res Ther. 2020. PMID: 33066807 Free PMC article. Review.
3,667 results