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NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis.
Sengupta D, Zeng L, Li Y, Hausmann S, Ghosh D, Yuan G, Nguyen TN, Lyu R, Caporicci M, Morales Benitez A, Coles GL, Kharchenko V, Czaban I, Azhibek D, Fischle W, Jaremko M, Wistuba II, Sage J, Jaremko Ł, Li W, Mazur PK, Gozani O. Sengupta D, et al. Among authors: kharchenko v. Mol Cell. 2021 Nov 4;81(21):4481-4492.e9. doi: 10.1016/j.molcel.2021.08.034. Epub 2021 Sep 22. Mol Cell. 2021. PMID: 34555356 Free PMC article.
Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
Yuan G, Flores NM, Hausmann S, Lofgren SM, Kharchenko V, Angulo-Ibanez M, Sengupta D, Lu X, Czaban I, Azhibek D, Vicent S, Fischle W, Jaremko M, Fang B, Wistuba II, Chua KF, Roth JA, Minna JD, Shao NY, Jaremko Ł, Mazur PK, Gozani O. Yuan G, et al. Among authors: kharchenko v. Nature. 2021 Feb;590(7846):504-508. doi: 10.1038/s41586-020-03170-y. Epub 2021 Feb 3. Nature. 2021. PMID: 33536620 Free PMC article.
Increased slow dynamics defines ligandability of BTB domains.
Kharchenko V, Linhares BM, Borregard M, Czaban I, Grembecka J, Jaremko M, Cierpicki T, Jaremko Ł. Kharchenko V, et al. Nat Commun. 2022 Nov 16;13(1):6989. doi: 10.1038/s41467-022-34599-6. Nat Commun. 2022. PMID: 36384931 Free PMC article.
429 results