Pehl U - Search Results

1

Molecular basis of human ATM kinase inhibition.

Stakyte K, Rotheneder M, Lammens K, Bartho JD, Grädler U, Fuchß T, Pehl U, Alt A, van de Logt E, Hopfner KP. Stakyte K, et al. Among authors: pehl u. Nat Struct Mol Biol. 2021 Oct;28(10):789-798. doi: 10.1038/s41594-021-00654-x. Epub 2021 Sep 23. Nat Struct Mol Biol. 2021. PMID: 34556870

2

A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies.

Zimmermann A, Zenke FT, Chiu LY, Dahmen H, Pehl U, Fuchss T, Grombacher T, Blume B, Vassilev LT, Blaukat A. Zimmermann A, et al. Among authors: pehl u. Mol Cancer Ther. 2022 Jun 1;21(6):859-870. doi: 10.1158/1535-7163.MCT-21-0934. Mol Cancer Ther. 2022. PMID: 35405736 Free PMC article.

3

Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.

Dorsch D, Schadt O, Stieber F, Meyring M, Grädler U, Bladt F, Friese-Hamim M, Knühl C, Pehl U, Blaukat A. Dorsch D, et al. Among authors: pehl u. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1597-602. doi: 10.1016/j.bmcl.2015.02.002. Epub 2015 Feb 16. Bioorg Med Chem Lett. 2015. PMID: 25736998

4

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.

Zenke FT, Zimmermann A, Sirrenberg C, Dahmen H, Kirkin V, Pehl U, Grombacher T, Wilm C, Fuchss T, Amendt C, Vassilev LT, Blaukat A. Zenke FT, et al. Among authors: pehl u. Mol Cancer Ther. 2020 May;19(5):1091-1101. doi: 10.1158/1535-7163.MCT-19-0734. Epub 2020 Mar 27. Mol Cancer Ther. 2020. PMID: 32220971

5

EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors.

Bladt F, Faden B, Friese-Hamim M, Knuehl C, Wilm C, Fittschen C, Grädler U, Meyring M, Dorsch D, Jaehrling F, Pehl U, Stieber F, Schadt O, Blaukat A. Bladt F, et al. Among authors: pehl u. Clin Cancer Res. 2013 Jun 1;19(11):2941-51. doi: 10.1158/1078-0432.CCR-12-3247. Epub 2013 Apr 3. Clin Cancer Res. 2013. PMID: 23553846

6

Illuminating a Dark Kinase: Structure-Guided Design, Synthesis, and Evaluation of a Potent Nek1 Inhibitor and Its Effects on the Embryonic Zebrafish Pronephros.

Baumann G, Meckel T, Böhm K, Shih YH, Dickhaut M, Reichardt T, Pilakowski J, Pehl U, Schmidt B. Baumann G, et al. Among authors: pehl u. J Med Chem. 2022 Jan 27;65(2):1265-1282. doi: 10.1021/acs.jmedchem.0c02118. Epub 2021 Mar 16. J Med Chem. 2022. PMID: 35081715

7

Integration of an In Situ MALDI-Based High-Throughput Screening Process: A Case Study with Receptor Tyrosine Kinase c-MET.

Beeman K, Baumgärtner J, Laubenheimer M, Hergesell K, Hoffmann M, Pehl U, Fischer F, Pieck JC. Beeman K, et al. Among authors: pehl u. SLAS Discov. 2017 Dec;22(10):1203-1210. doi: 10.1177/2472555217727701. Epub 2017 Aug 18. SLAS Discov. 2017. PMID: 28820955 Free article.

8

Cholinergic signal transduction in the mouse sphenopalatine ganglion.

Rafalzik S, Pehl U, Ott D, Strotmann J, Wolff M, Gerstberger R. Rafalzik S, et al. Among authors: pehl u. Brain Res. 2008 Nov 19;1241:42-55. doi: 10.1016/j.brainres.2008.08.095. Epub 2008 Sep 16. Brain Res. 2008. PMID: 18817758

9

Olfactory receptor expressed in ganglia of the autonomic nervous system.

Weber M, Pehl U, Breer H, Strotmann J. Weber M, et al. Among authors: pehl u. J Neurosci Res. 2002 Apr 15;68(2):176-84. doi: 10.1002/jnr.10164. J Neurosci Res. 2002. PMID: 11948663

10

Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea-pigs.

Roth J, Hübschle T, Pehl U, Ross G, Gerstberger R. Roth J, et al. Among authors: pehl u. Pflugers Arch. 2002 Jan;443(3):411-7. doi: 10.1007/s004240100718. Epub 2001 Oct 10. Pflugers Arch. 2002. PMID: 11810211

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