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Page 1
Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomised, Placebo-Controlled, Phase 1/2 Trial.
Pitisuttithum P, Luvira V, Lawpoolsri S, Muangnoicharoen S, Kamolratanakul S, Sivakorn C, Narakorn P, Surichan S, Prangpratanporn S, Puksuriwong S, Lamola S, Mercer LD, Raghunandan R, Sun W, Liu Y, Carreño JM, Scharf R, Phumratanaprapin W, Amanat F, Gagnon L, Hsieh CL, Kaweepornpoj R, Khan S, Lal M, McCroskery S, McLellan J, Mena I, Meseck M, Phonrat B, Sabmee Y, Singchareon R, Slamanig S, Suthepakul N, Tcheou J, Thantamnu N, Theerasurakarn S, Tran S, Vilasmongkolchai T, White JA, Garcia-Sastre A, Palese P, Krammer F, Poopipatpol K, Wirachwong P, Hjorth R, Innis BL. Pitisuttithum P, et al. medRxiv [Preprint]. 2021 Sep 22:2021.09.17.21263758. doi: 10.1101/2021.09.17.21263758. medRxiv. 2021. Update in: EClinicalMedicine. 2022 Mar 08;45:101323. doi: 10.1016/j.eclinm.2022.101323 PMID: 34580673 Free PMC article. Updated. Preprint.
Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.
Rathnasinghe R, Salvatore M, Zheng H, Jangra S, Kehrer T, Mena I, Schotsaert M, Muster T, Palese P, García-Sastre A. Rathnasinghe R, et al. bioRxiv [Preprint]. 2021 Apr 28:2021.04.28.441797. doi: 10.1101/2021.04.28.441797. bioRxiv. 2021. Update in: Sci Rep. 2021 Nov 12;11(1):22164. doi: 10.1038/s41598-021-01780-8 PMID: 33948589 Free PMC article. Updated. Preprint.
Safety and immunogenicity of a live recombinant Newcastle disease virus-based COVID-19 vaccine (Patria) administered via the intramuscular or intranasal route: Interim results of a non-randomized open label phase I trial in Mexico.
Ponce-de-León S, Torres M, Soto-Ramírez LE, Calva JJ, Santillán-Doherty P, Carranza-Salazar DE, Carreño JM, Carranza C, Juárez E, Carreto-Binaghi LE, Ramírez-Martínez L, Paz-De la Rosa G, Vigueras-Moreno R, Ortiz-Stern A, López-Vidal Y, Macías AE, Torres-Flores J, Rojas-Martínez O, Suárez-Martínez A, Peralta-Sánchez G, Kawabata H, González-Domínguez I, Martínez-Guevara JL, Sun W, Sarfati-Mizrahi D, Soto-Priante E, Chagoya-Cortés HE, López-Macías C, Castro-Peralta F, Palese P, García-Sastre A, Krammer F, Lozano-Dubernard B. Ponce-de-León S, et al. medRxiv [Preprint]. 2022 Feb 9:2022.02.08.22270676. doi: 10.1101/2022.02.08.22270676. medRxiv. 2022. PMID: 35169806 Free PMC article. Preprint.
Trivalent NDV-HXP-S vaccine protects against phylogenetically distant SARS-CoV-2 variants of concern in mice.
González-Domínguez I, Martínez JL, Slamanig S, Lemus N, Liu Y, Lai TY, Carreño JM, Singh A G, Singh B G, Schotsaert M, Mena I, McCroskery S, Coughlan L, Krammer F, García-Sastre A, Palese P, Sun W. González-Domínguez I, et al. bioRxiv [Preprint]. 2022 Mar 22:2022.03.21.485247. doi: 10.1101/2022.03.21.485247. bioRxiv. 2022. Update in: Microbiol Spectr. 2022 Jun 29;10(3):e0153822. doi: 10.1128/spectrum.01538-22 PMID: 35350201 Free PMC article. Updated. Preprint.
Phase II study on the safety and immunogenicity of single-dose intramuscular or intranasal administration of the AVX/COVID-12 "Patria" recombinant Newcastle disease virus vaccine as a heterologous booster against COVID-19 in Mexico.
López-Macías C, Torres M, Armenta-Copca B, Wacher NH, Castro-Castrezana L, Colli-Domínguez AA, Rivera-Hernández T, Torres-Flores A, Damián-Hernández M, Ramírez-Martínez L, la Rosa GP, Rojas-Martínez O, Suárez-Martínez A, Peralta-Sánchez G, Carranza C, Juárez E, Zamudio-Meza H, Carreto-Binaghi LE, Viettri M, Romero-Rodríguez D, Palencia A, Reyna-Rosas E, Márquez-García JE, Sarfati-Mizrahi D, Sun W, Chagoya-Cortés HE, Castro-Peralta F, Palese P, Krammer F, García-Sastre A, Lozano-Dubernard B. López-Macías C, et al. Among authors: garcia sastre a. Vaccine. 2025 Jan 1;43(Pt 2):126511. doi: 10.1016/j.vaccine.2024.126511. Epub 2024 Nov 10. Vaccine. 2025. PMID: 39527880 Free article. Clinical Trial.
Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants.
Muñoz-Alía MÁ, Nace RA, Balakrishnan B, Zhang L, Packiriswamy N, Singh G, Warang P, Mena I, Narjari R, Vandergaast R, García-Sastre A, Schotsaert M, Russell SJ. Muñoz-Alía MÁ, et al. bioRxiv [Preprint]. 2022 Dec 16:2022.12.16.520799. doi: 10.1101/2022.12.16.520799. bioRxiv. 2022. Update in: mBio. 2024 Feb 14;15(2):e0292823. doi: 10.1128/mbio.02928-23 PMID: 36561187 Free PMC article. Updated. Preprint.
Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection.
Sircy LM, Ramstead AG, Joshi H, Baessler A, Mena I, García-Sastre A, Williams MA, Scott Hale J. Sircy LM, et al. bioRxiv [Preprint]. 2023 Aug 31:2023.08.29.555253. doi: 10.1101/2023.08.29.555253. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Sep 16;20(9):e1011639. doi: 10.1371/journal.ppat.1011639 PMID: 37693425 Free PMC article. Updated. Preprint.
Characteristics of Lung Cancer Patients With Asymptomatic or Undiagnosed SARS-CoV-2 Infections.
Somisetty M, Mack PC, Hsu CY, Huang Y, Gomez JE, Rodilla AM, Cagan J, Tavolacci SC, Carreño JM, Brody R, Moore AC, King JC, Rohs NC, Rolfo C, Bunn PA, Minna JD, Bhalla S, Krammer F, García-Sastre A, Figueiredo JC, Kazemian E, Reckamp KL, Merchant AA, Nadri M, Ahmed R, Ramalingam SS, Shyr Y, Hirsch FR, Gerber DE. Somisetty M, et al. Clin Lung Cancer. 2024 Nov;25(7):612-618. doi: 10.1016/j.cllc.2024.07.007. Epub 2024 Jul 20. Clin Lung Cancer. 2024. PMID: 39122606
Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.
Varona JF, Landete P, Lopez-Martin JA, Estrada V, Paredes R, Guisado-Vasco P, de Orueta LF, Torralba M, Fortún J, Vates R, Barberán J, Clotet B, Ancochea J, Carnevali D, Cabello N, Porras L, Gijón P, Monereo A, Abad D, Zúñiga S, Sola I, Rodon J, Izquierdo-Useros N, Fudio S, Pontes MJ, de Rivas B, Girón de Velasco P, Sopesén B, Nieto A, Gómez J, Avilés P, Lubomirov R, White KM, Rosales R, Yildiz S, Reuschl AK, Thorne LG, Jolly C, Towers GJ, Zuliani-Alvarez L, Bouhaddou M, Obernier K, Enjuanes L, Fernández-Sousa JM; Plitidepsin – COVID - 19 Study Group; Krogan NJ, Jimeno JM, García-Sastre A. Varona JF, et al. medRxiv [Preprint]. 2021 May 25:2021.05.25.21257505. doi: 10.1101/2021.05.25.21257505. medRxiv. 2021. Update in: Life Sci Alliance. 2022 Jan 10;5(4):e202101200. doi: 10.26508/lsa.202101200 PMID: 34075384 Free PMC article. Updated. Preprint.
Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters.
García-Bernalt Diego J, Singh G, Jangra S, Handrejk K, Laporte M, Chang LA, El Zahed SS, Pache L, Chang MW, Warang P, Aslam S, Mena I, Webb BT, Benner C, García-Sastre A, Schotsaert M. García-Bernalt Diego J, et al. bioRxiv [Preprint]. 2023 May 23:2023.05.22.541294. doi: 10.1101/2023.05.22.541294. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Jan 10;20(1):e1011805. doi: 10.1371/journal.ppat.1011805 PMID: 37425792 Free PMC article. Updated. Preprint.
828 results