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Structural basis for UFM1 transfer from UBA5 to UFC1.
Kumar M, Padala P, Fahoum J, Hassouna F, Tsaban T, Zoltsman G, Banerjee S, Cohen-Kfir E, Dessau M, Rosenzweig R, Isupov MN, Schueler-Furman O, Wiener R. Kumar M, et al. Among authors: hassouna f. Nat Commun. 2021 Sep 29;12(1):5708. doi: 10.1038/s41467-021-25994-6. Nat Commun. 2021. PMID: 34588452 Free PMC article.
Trans-binding of UFM1 to UBA5 stimulates UBA5 homodimerization and ATP binding.
Mashahreh B, Hassouna F, Soudah N, Cohen-Kfir E, Strulovich R, Haitin Y, Wiener R. Mashahreh B, et al. Among authors: hassouna f. FASEB J. 2018 May;32(5):2794-2802. doi: 10.1096/fj.201701057R. Epub 2018 Jan 8. FASEB J. 2018. PMID: 29295865
Our results make a connection between the binding of UFM1 to UBA5 and the latter's affinity to ATP, so we propose a novel mechanism for the regulation of ATP's binding to E1.-Mashahreh, B., Hassouna, F., Soudah, N., Cohen-Kfir, E., Strulovich, R., Haitin, Y., Wiener …
Our results make a connection between the binding of UFM1 to UBA5 and the latter's affinity to ATP, so we propose a novel mechanism for the …
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair.
Amar-Schwartz A, Ben Hur V, Jbara A, Cohen Y, Barnabas GD, Arbib E, Siegfried Z, Mashahreh B, Hassouna F, Shilo A, Abu-Odeh M, Berger M, Wiener R, Aqeilan R, Geiger T, Karni R. Amar-Schwartz A, et al. Among authors: hassouna f. Elife. 2022 Oct 3;11:e79128. doi: 10.7554/eLife.79128. Elife. 2022. PMID: 36189922 Free PMC article.
25 results