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Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation.
Ramadan M, A M M Elshaier Y, Aly AA, Abdel-Aziz M, Fathy HM, Brown AB, Pridgen JR, Dalby KN, Kaoud TS. Ramadan M, et al. Among authors: a m m elshaier y. Bioorg Chem. 2021 Nov;116:105344. doi: 10.1016/j.bioorg.2021.105344. Epub 2021 Sep 20. Bioorg Chem. 2021. PMID: 34598088
FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2.
Mostafa A, Kandeil A, A M M Elshaier Y, Kutkat O, Moatasim Y, Rashad AA, Shehata M, Gomaa MR, Mahrous N, Mahmoud SH, GabAllah M, Abbas H, Taweel AE, Kayed AE, Kamel MN, Sayes ME, Mahmoud DB, El-Shesheny R, Kayali G, Ali MA. Mostafa A, et al. Among authors: a m m elshaier y. Pharmaceuticals (Basel). 2020 Dec 4;13(12):443. doi: 10.3390/ph13120443. Pharmaceuticals (Basel). 2020. PMID: 33291642 Free PMC article.
Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potentials antibacterial and anti-SARS-CoV-2 activities.
Refaey MS, A A Fayed M, Kutkat O, Moatasim Y, Sameh Tolba N, Anis A, Elshorbagy AM, Nassar K, A M Abouzid K, A M M Elshaier Y, El-Badawy MF. Refaey MS, et al. Among authors: a m m elshaier y. Arab J Chem. 2023 Jul;16(7):104813. doi: 10.1016/j.arabjc.2023.104813. Epub 2023 Mar 18. Arab J Chem. 2023. PMID: 36969951 Free PMC article.
Design, synthesis, modeling studies and biological evaluation of pyrazole derivatives linked to oxime and nitrate moieties as nitric oxide donor selective COX-2 and aromatase inhibitors with dual anti-inflammatory and anti-neoplastic activities.
A A Fadaly W, A M M Elshaier Y, T M Nemr M, R A Abdellatif K. A A Fadaly W, et al. Among authors: a m m elshaier y. Bioorg Chem. 2023 May;134:106428. doi: 10.1016/j.bioorg.2023.106428. Epub 2023 Feb 18. Bioorg Chem. 2023. PMID: 36893546