Aly AA - Search Results

1

Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation.

Ramadan M, A M M Elshaier Y, Aly AA, Abdel-Aziz M, Fathy HM, Brown AB, Pridgen JR, Dalby KN, Kaoud TS. Ramadan M, et al. Among authors: aly aa. Bioorg Chem. 2021 Nov;116:105344. doi: 10.1016/j.bioorg.2021.105344. Epub 2021 Sep 20. Bioorg Chem. 2021. PMID: 34598088

2

Thieno[2,3-d]pyrimidines in the synthesis of antitumor and antioxidant agents.

Aly AA, Brown AB, Ramadan M, Gamal-Eldeen AM, Abdel-Aziz M, Abuo-Rahma Gel-D, Radwan MF. Aly AA, et al. Arch Pharm (Weinheim). 2010 May;343(5):301-9. doi: 10.1002/ardp.200900245. Arch Pharm (Weinheim). 2010. PMID: 20232374

3

Regioselective formation of 1,2,4-triazoles by the reaction of amidrazones in the presence of diethyl azodicarboxylate and catalyzed by triethylamine.

Aly AA, Hassan AA, Mohamed NK, Ramadan M, Brown AB, Abd El-Aal AS, Bräse S, Nieger M. Aly AA, et al. Mol Divers. 2019 Feb;23(1):195-203. doi: 10.1007/s11030-018-9868-6. Epub 2018 Aug 13. Mol Divers. 2019. PMID: 30105556

4

Synthesis of novel 1,2-bis-quinolinyl-1,4-naphthoquinones: ERK2 inhibition, cytotoxicity and molecular docking studies.

Aly AA, El-Sheref EM, Bakheet MEM, Mourad MAE, Brown AB, Bräse S, Nieger M, Ibrahim MAA. Aly AA, et al. Bioorg Chem. 2018 Dec;81:700-712. doi: 10.1016/j.bioorg.2018.09.017. Epub 2018 Sep 14. Bioorg Chem. 2018. PMID: 30268050

5

Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma.

Aly AA, El-Sheref EM, Bakheet MEM, Mourad MAE, Bräse S, Ibrahim MAA, Nieger M, Garvalov BK, Dalby KN, Kaoud TS. Aly AA, et al. Bioorg Chem. 2019 Feb;82:290-305. doi: 10.1016/j.bioorg.2018.10.044. Epub 2018 Oct 23. Bioorg Chem. 2019. PMID: 30396063 Free PMC article.

6

Design, synthesis, and DNA interaction studies of furo-imidazo[3.3.3]propellane derivatives: Potential anticancer agents.

Hassan AA, Aly AA, Mohamed NK, El Shaieb KM, Makhlouf MM, Abdelhafez EMN, Bräse S, Nieger M, Dalby KN, Kaoud TS. Hassan AA, et al. Among authors: aly aa. Bioorg Chem. 2019 Apr;85:585-599. doi: 10.1016/j.bioorg.2019.02.027. Epub 2019 Feb 13. Bioorg Chem. 2019. PMID: 30878891 Free PMC article.

7

Novel Pyrazoloquinolin-2-ones: Design, synthesis, docking studies, and biological evaluation as antiproliferative EGFR-TK inhibitors.

Elbastawesy MAI, Aly AA, Ramadan M, Elshaier YAMM, Youssif BGM, Brown AB, El-Din A Abuo-Rahma G. Elbastawesy MAI, et al. Among authors: aly aa. Bioorg Chem. 2019 Sep;90:103045. doi: 10.1016/j.bioorg.2019.103045. Epub 2019 Jun 8. Bioorg Chem. 2019. PMID: 31212178

8

Functionalized 1,3-Thiazolidin-4-Ones from 2-Oxo-Acenaphthoquinylidene- and [2.2]Paracyclophanylidene-Thiosemicarbazones.

Aly AA, Mohamed NK, Hassan AA, El-Shaieb KM, Makhlouf MM, Bräse S, Nieger M, Brown AB. Aly AA, et al. Molecules. 2019 Aug 23;24(17):3069. doi: 10.3390/molecules24173069. Molecules. 2019. PMID: 31450781 Free PMC article.

9

Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones.

Aly AA, Hassan AA, Mohamed NK, El-Haleem LEA, Bräse S, Polamo M, Nieger M, Brown AB. Aly AA, et al. Molecules. 2019 Oct 21;24(20):3782. doi: 10.3390/molecules24203782. Molecules. 2019. PMID: 31640196 Free PMC article.

10

New quinoline-2-one/pyrazole derivatives; design, synthesis, molecular docking, anti-apoptotic evaluation, and caspase-3 inhibition assay.

Aly AA, Sayed SM, Abdelhafez EMN, Abdelhafez SMN, Abdelzaher WY, Raslan MA, Ahmed AE, Thabet K, El-Reedy AAM, Brown AB, Bräse S. Aly AA, et al. Bioorg Chem. 2020 Jan;94:103348. doi: 10.1016/j.bioorg.2019.103348. Epub 2019 Oct 9. Bioorg Chem. 2020. PMID: 31699387

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