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102 results

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Page 1
Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures.
Byrne EH, Farcasanu M, Bloom SM, Xulu N, Xu J, Hykes BL Jr, Mafunda NA, Hayward MR, Dong M, Dong KL, Gumbi T, Ceasar FX, Ismail N, Ndung'u T, Gosmann C, Ghebremichael MS, Handley SA, Mitchell CM, Villani AC, Kwon DS. Byrne EH, et al. Among authors: handley sa. Front Cell Infect Microbiol. 2021 Sep 16;11:733619. doi: 10.3389/fcimb.2021.733619. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34604114 Free PMC article.
Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome.
Monaco CL, Gootenberg DB, Zhao G, Handley SA, Ghebremichael MS, Lim ES, Lankowski A, Baldridge MT, Wilen CB, Flagg M, Norman JM, Keller BC, Luévano JM, Wang D, Boum Y, Martin JN, Hunt PW, Bangsberg DR, Siedner MJ, Kwon DS, Virgin HW. Monaco CL, et al. Among authors: handley sa. Cell Host Microbe. 2016 Mar 9;19(3):311-22. doi: 10.1016/j.chom.2016.02.011. Cell Host Microbe. 2016. PMID: 26962942 Free PMC article.
Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women.
Gosmann C, Anahtar MN, Handley SA, Farcasanu M, Abu-Ali G, Bowman BA, Padavattan N, Desai C, Droit L, Moodley A, Dong M, Chen Y, Ismail N, Ndung'u T, Ghebremichael MS, Wesemann DR, Mitchell C, Dong KL, Huttenhower C, Walker BD, Virgin HW, Kwon DS. Gosmann C, et al. Among authors: handley sa. Immunity. 2017 Jan 17;46(1):29-37. doi: 10.1016/j.immuni.2016.12.013. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087240 Free PMC article.
Tropism for tuft cells determines immune promotion of norovirus pathogenesis.
Wilen CB, Lee S, Hsieh LL, Orchard RC, Desai C, Hykes BL Jr, McAllaster MR, Balce DR, Feehley T, Brestoff JR, Hickey CA, Yokoyama CC, Wang YT, MacDuff DA, Kreamalmayer D, Howitt MR, Neil JA, Cadwell K, Allen PM, Handley SA, van Lookeren Campagne M, Baldridge MT, Virgin HW. Wilen CB, et al. Among authors: handley sa. Science. 2018 Apr 13;360(6385):204-208. doi: 10.1126/science.aar3799. Science. 2018. PMID: 29650672 Free PMC article.
Effect of Antibiotic-Mediated Microbiome Modulation on Rotavirus Vaccine Immunogenicity: A Human, Randomized-Control Proof-of-Concept Trial.
Harris VC, Haak BW, Handley SA, Jiang B, Velasquez DE, Hykes BL Jr, Droit L, Berbers GAM, Kemper EM, van Leeuwen EMM, Boele van Hensbroek M, Wiersinga WJ. Harris VC, et al. Among authors: handley sa. Cell Host Microbe. 2018 Aug 8;24(2):197-207.e4. doi: 10.1016/j.chom.2018.07.005. Cell Host Microbe. 2018. PMID: 30092197 Free PMC article. Clinical Trial.
A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.
Lee S, Liu H, Wilen CB, Sychev ZE, Desai C, Hykes BL Jr, Orchard RC, McCune BT, Kim KW, Nice TJ, Handley SA, Baldridge MT, Amarasinghe GK, Virgin HW. Lee S, et al. Among authors: handley sa. Cell Host Microbe. 2019 Jun 12;25(6):845-857.e5. doi: 10.1016/j.chom.2019.04.005. Epub 2019 May 23. Cell Host Microbe. 2019. PMID: 31130511 Free PMC article.
The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
Winkler ES, Shrihari S, Hykes BL Jr, Handley SA, Andhey PS, Huang YS, Swain A, Droit L, Chebrolu KK, Mack M, Vanlandingham DL, Thackray LB, Cella M, Colonna M, Artyomov MN, Stappenbeck TS, Diamond MS. Winkler ES, et al. Among authors: handley sa. Cell. 2020 Aug 20;182(4):901-918.e18. doi: 10.1016/j.cell.2020.06.029. Epub 2020 Jul 14. Cell. 2020. PMID: 32668198 Free PMC article.
UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages.
Balce DR, Wang YT, McAllaster MR, Dunlap BF, Orvedahl A, Hykes BL Jr, Droit L, Handley SA, Wilen CB, Doench JG, Orchard RC, Stallings CL, Virgin HW. Balce DR, et al. Among authors: handley sa. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2011763118. doi: 10.1073/pnas.2011763118. Proc Natl Acad Sci U S A. 2021. PMID: 33372156 Free PMC article.
HIV-associated gut microbial alterations are dependent on host and geographic context.
Rocafort M, Gootenberg DB, Luévano JM Jr, Paer JM, Hayward MR, Bramante JT, Ghebremichael MS, Xu J, Rogers ZH, Munoz AR, Okello S, Kim JH, Sentongo R, Wagubi R, Lankowski A, Maruapula S, Zhao G, Handley SA, Mosepele M, Siedner MJ, Kwon DS. Rocafort M, et al. Among authors: handley sa. Nat Commun. 2024 Feb 5;15(1):1055. doi: 10.1038/s41467-023-44566-4. Nat Commun. 2024. PMID: 38316748 Free PMC article.
102 results