Barilone N - Search Results

1

A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG.

Lisa MN, Sogues A, Barilone N, Baumgart M, Gil M, Graña M, Durán R, Biondi RM, Bellinzoni M, Bott M, Alzari PM. Lisa MN, et al. Among authors: barilone n. mBio. 2021 Oct 26;12(5):e0171721. doi: 10.1128/mBio.01717-21. Epub 2021 Oct 5. mBio. 2021. PMID: 34607462 Free PMC article.

2

The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation.

Wagner T, Alexandre M, Duran R, Barilone N, Wehenkel A, Alzari PM, Bellinzoni M. Wagner T, et al. Among authors: barilone n. Proteins. 2015 May;83(5):982-8. doi: 10.1002/prot.24754. Epub 2015 Mar 25. Proteins. 2015. PMID: 25586004 Free article.

3

Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis.

Lisa MN, Gil M, André-Leroux G, Barilone N, Durán R, Biondi RM, Alzari PM. Lisa MN, et al. Among authors: barilone n. Structure. 2015 Jun 2;23(6):1039-48. doi: 10.1016/j.str.2015.04.001. Epub 2015 May 7. Structure. 2015. PMID: 25960409 Free article.

4

A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase).

Wagner T, Barilone N, Alzari PM, Bellinzoni M. Wagner T, et al. Among authors: barilone n. Biochem J. 2014 Feb 1;457(3):425-34. doi: 10.1042/BJ20131142. Biochem J. 2014. PMID: 24171907

5

The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.

Lisa MN, Wagner T, Alexandre M, Barilone N, Raynal B, Alzari PM, Bellinzoni M. Lisa MN, et al. Among authors: barilone n. FEBS J. 2017 Feb;284(4):602-614. doi: 10.1111/febs.14003. Epub 2017 Jan 29. FEBS J. 2017. PMID: 28054744 Free article.

6

Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.

Wagner T, André-Leroux G, Hindie V, Barilone N, Lisa MN, Hoos S, Raynal B, Vulliez-Le Normand B, O'Hare HM, Bellinzoni M, Alzari PM. Wagner T, et al. Among authors: barilone n. Sci Signal. 2019 May 7;12(580):eaav9504. doi: 10.1126/scisignal.aav9504. Sci Signal. 2019. PMID: 31064884

7

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria.

Wehenkel A, Fernandez P, Bellinzoni M, Catherinot V, Barilone N, Labesse G, Jackson M, Alzari PM. Wehenkel A, et al. Among authors: barilone n. FEBS Lett. 2006 May 29;580(13):3018-22. doi: 10.1016/j.febslet.2006.04.046. Epub 2006 Apr 27. FEBS Lett. 2006. PMID: 16674948 Free article.

8

The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth.

Fernandez P, Saint-Joanis B, Barilone N, Jackson M, Gicquel B, Cole ST, Alzari PM. Fernandez P, et al. Among authors: barilone n. J Bacteriol. 2006 Nov;188(22):7778-84. doi: 10.1128/JB.00963-06. Epub 2006 Sep 15. J Bacteriol. 2006. PMID: 16980473 Free PMC article.

9

Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis.

Mechaly AE, Haouz A, Miras I, Barilone N, Weber P, Shepard W, Alzari PM, Bellinzoni M. Mechaly AE, et al. Among authors: barilone n. FEBS Lett. 2012 Jun 4;586(11):1606-11. doi: 10.1016/j.febslet.2012.04.034. Epub 2012 May 3. FEBS Lett. 2012. PMID: 22561013 Free article.

10

GarA is an essential regulator of metabolism in Mycobacterium tuberculosis.

Ventura M, Rieck B, Boldrin F, Degiacomi G, Bellinzoni M, Barilone N, Alzaidi F, Alzari PM, Manganelli R, O'Hare HM. Ventura M, et al. Among authors: barilone n. Mol Microbiol. 2013 Oct;90(2):356-66. doi: 10.1111/mmi.12368. Epub 2013 Sep 8. Mol Microbiol. 2013. PMID: 23962235 Free article.

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