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A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
Chen J, Lambo ME, Ge X, Dearborn JT, Liu Y, McCullough KB, Swift RG, Tabachnick DR, Tian L, Noguchi K, Garbow JR, Constantino JN, Gabel HW, Hengen KB, Maloney SE, Dougherty JD. Chen J, et al. Among authors: gabel hw. Neuron. 2021 Dec 1;109(23):3775-3792.e14. doi: 10.1016/j.neuron.2021.09.009. Epub 2021 Oct 5. Neuron. 2021. PMID: 34614421 Free PMC article.
Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
Smith AM, LaValle TA, Shinawi M, Ramakrishnan SM, Abel HJ, Hill CA, Kirkland NM, Rettig MP, Helton NM, Heath SE, Ferraro F, Chen DY, Adak S, Semenkovich CF, Christian DL, Martin JR, Gabel HW, Miller CA, Ley TJ. Smith AM, et al. Among authors: gabel hw. Nat Commun. 2021 Jul 27;12(1):4549. doi: 10.1038/s41467-021-24800-7. Nat Commun. 2021. PMID: 34315901 Free PMC article.
APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain.
Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. Ferguson CJ, et al. Among authors: gabel hw. Mol Cell. 2022 Jan 6;82(1):90-105.e13. doi: 10.1016/j.molcel.2021.11.031. Epub 2021 Dec 22. Mol Cell. 2022. PMID: 34942119 Free PMC article.
Emerging Insights into the Distinctive Neuronal Methylome.
Clemens AW, Gabel HW. Clemens AW, et al. Among authors: gabel hw. Trends Genet. 2020 Nov;36(11):816-832. doi: 10.1016/j.tig.2020.07.009. Epub 2020 Aug 21. Trends Genet. 2020. PMID: 32839016 Free PMC article. Review.
The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain.
Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman JV, Reddy NC, Majidi SP, Wu DY, Smith SE, Godec A, Oldenborg A, Gabel HW, Zhao G, Bonni S, Bonni A. Chen X, et al. Among authors: gabel hw. J Neurosci. 2019 Jan 2;39(1):44-62. doi: 10.1523/JNEUROSCI.0688-18.2018. Epub 2018 Nov 13. J Neurosci. 2019. PMID: 30425119 Free PMC article.
Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs.
Cates K, McCoy MJ, Kwon JS, Liu Y, Abernathy DG, Zhang B, Liu S, Gontarz P, Kim WK, Chen S, Kong W, Ho JN, Burbach KF, Gabel HW, Morris SA, Yoo AS. Cates K, et al. Among authors: gabel hw. Cell Stem Cell. 2021 Jan 7;28(1):127-140.e9. doi: 10.1016/j.stem.2020.08.015. Epub 2020 Sep 21. Cell Stem Cell. 2021. PMID: 32961143 Free PMC article.
42 results