Singh L - Search Results

1

The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion.

Chen YJ, Cui Y, Singh L, Wulff H. Chen YJ, et al. Among authors: singh l. Ann Clin Transl Neurol. 2021 Oct;8(10):2070-2082. doi: 10.1002/acn3.51456. Epub 2021 Oct 7. Ann Clin Transl Neurol. 2021. PMID: 34617690 Free PMC article.

2

Chasing the Elusive Benzofuran Impurity of the THR Antagonist NH-3: Synthesis, Isotope Labeling, and Biological Activity.

Singh L, Pressly B, Mengeling BJ, Fettinger JC, Furlow JD, Lein PJ, Wulff H, Singh V. Singh L, et al. Among authors: singh v. J Org Chem. 2016 Mar 4;81(5):1870-6. doi: 10.1021/acs.joc.5b02665. Epub 2016 Feb 18. J Org Chem. 2016. PMID: 26849160

3

A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling.

Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. Mengeling BJ, et al. Among authors: singh l, singh v. Aquat Toxicol. 2017 Sep;190:1-10. doi: 10.1016/j.aquatox.2017.06.019. Epub 2017 Jun 21. Aquat Toxicol. 2017. PMID: 28662416 Free PMC article.

4

Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease.

Jin LW, Lucente JD, Nguyen HM, Singh V, Singh L, Chavez M, Bushong T, Wulff H, Maezawa I. Jin LW, et al. Among authors: singh l, singh v. Ann Clin Transl Neurol. 2019 Mar 18;6(4):723-738. doi: 10.1002/acn3.754. eCollection 2019 Apr. Ann Clin Transl Neurol. 2019. PMID: 31019997 Free PMC article.

5

The Trials and Tribulations of Structure Assisted Design of K_Ca Channel Activators.

Shim H, Brown BM, Singh L, Singh V, Fettinger JC, Yarov-Yarovoy V, Wulff H. Shim H, et al. Among authors: singh l, singh v. Front Pharmacol. 2019 Sep 20;10:972. doi: 10.3389/fphar.2019.00972. eCollection 2019. Front Pharmacol. 2019. PMID: 31616290 Free PMC article.

6

Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice.

Pressly B, Vasylieva N, Barnych B, Singh V, Singh L, Bruun DA, Hwang SH, Chen YJ, Fettinger JC, Johnnides S, Lein PJ, Yang J, Hammock BD, Wulff H. Pressly B, et al. Among authors: singh l, singh v. Arch Toxicol. 2020 Jun;94(6):1995-2007. doi: 10.1007/s00204-020-02728-z. Epub 2020 Apr 1. Arch Toxicol. 2020. PMID: 32239239 Free PMC article.

7

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2.

Mundy PC, Werner A, Singh L, Singh V, Mendieta R, Patullo CE, Wulff H, Lein PJ. Mundy PC, et al. Among authors: singh l, singh v. Arch Toxicol. 2023 May;97(5):1355-1365. doi: 10.1007/s00204-023-03475-7. Epub 2023 Mar 13. Arch Toxicol. 2023. PMID: 36912926 Free PMC article.

8

Repurposing the K_Ca3.1 Blocker Senicapoc for Ischemic Stroke.

Lee RD, Chen YJ, Nguyen HM, Singh L, Dietrich CJ, Pyles BR, Cui Y, Weinstein JR, Wulff H. Lee RD, et al. Among authors: singh l. Transl Stroke Res. 2024 Jun;15(3):518-532. doi: 10.1007/s12975-023-01152-6. Epub 2023 Apr 24. Transl Stroke Res. 2024. PMID: 37088858 Free PMC article.

9

Immunocytoprotection after reperfusion with Kv1.3 inhibitors has an extended treatment window for ischemic stroke.

Lee RD, Chen YJ, Singh L, Nguyen HM, Wulff H. Lee RD, et al. Among authors: singh l. Front Pharmacol. 2023 Apr 25;14:1190476. doi: 10.3389/fphar.2023.1190476. eCollection 2023. Front Pharmacol. 2023. PMID: 37180699 Free PMC article.

10

Targeting endothelial K_Ca channels in vivo restores arterial and endothelial function in type 2 diabetic rats.

Mishra RC, Belke DD, Singh L, Wulff H, Braun AP. Mishra RC, et al. Among authors: singh l. Metabolism. 2024 Nov;160:156001. doi: 10.1016/j.metabol.2024.156001. Epub 2024 Aug 18. Metabolism. 2024. PMID: 39163925 Free article.

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