Specks U - Search Results

1

Circulating autoreactive proteinase 3+ B cells and tolerance checkpoints in ANCA-associated vasculitis.

Berti A, Hillion S, Hummel AM, Son YM, Chriti N, Peikert T, Carmona EM, Abdulahad WH, Heeringa P, Harris KM, St Clair EW, Brunetta P, Fervenza FC, Langford CA, Kallenberg CG, Merkel PA, Monach PA, Seo P, Spiera RF, Stone JH, Grandi G, Sun J, Pers JO, Specks U, Cornec D; RAVE-ITN Research Group. Berti A, et al. Among authors: specks u. JCI Insight. 2021 Nov 22;6(22):e150999. doi: 10.1172/jci.insight.150999. JCI Insight. 2021. PMID: 34618687 Free PMC article. Clinical Trial.

2

Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.

Specks U, Fass DN, Fautsch MP, Hummel AM, Viss MA. Specks U, et al. FEBS Lett. 1996 Jul 29;390(3):265-70. doi: 10.1016/0014-5793(96)00669-2. FEBS Lett. 1996. PMID: 8706874 Free article.

3

Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.

Jenne DE, Fröhlich L, Hummel AM, Specks U. Jenne DE, et al. Among authors: specks u. FEBS Lett. 1997 May 19;408(2):187-90. doi: 10.1016/s0014-5793(97)00418-3. FEBS Lett. 1997. PMID: 9187364 Free article.

4

Capture-ELISA based on recombinant PR3 is sensitive for PR3-ANCA testing and allows detection of PR3 and PR3-ANCA/PR3 immunecomplexes.

Sun J, Fass DN, Hudson JA, Viss MA, Wieslander J, Homburger HA, Specks U. Sun J, et al. Among authors: specks u. J Immunol Methods. 1998 Feb 1;211(1-2):111-23. doi: 10.1016/s0022-1759(97)00203-2. J Immunol Methods. 1998. PMID: 9617836

5

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide.

Sun J, Fass DN, Viss MA, Hummel AM, Tang H, Homburger HA, Specks U. Sun J, et al. Among authors: specks u. Clin Exp Immunol. 1998 Nov;114(2):320-6. doi: 10.1046/j.1365-2249.1998.00730.x. Clin Exp Immunol. 1998. PMID: 9822293 Free PMC article.

6

Recombinant proteinase 3 produced in different expression systems: recognition by anti-PR3 antibodies.

van der Geld YM, Oost-Kort W, Limburg PC, Specks U, Kallenberg CG. van der Geld YM, et al. Among authors: specks u. J Immunol Methods. 2000 Oct 20;244(1-2):117-31. doi: 10.1016/s0022-1759(00)00261-1. J Immunol Methods. 2000. PMID: 11033024

7

A disease-specific activity index for Wegener's granulomatosis: modification of the Birmingham Vasculitis Activity Score. International Network for the Study of the Systemic Vasculitides (INSSYS).

Stone JH, Hoffman GS, Merkel PA, Min YI, Uhlfelder ML, Hellmann DB, Specks U, Allen NB, Davis JC, Spiera RF, Calabrese LH, Wigley FM, Maiden N, Valente RM, Niles JL, Fye KH, McCune JW, St Clair EW, Luqmani RA; International Network for the Study of the Systemic Vasculitides (INSSYS). Stone JH, et al. Among authors: specks u. Arthritis Rheum. 2001 Apr;44(4):912-20. doi: 10.1002/1529-0131(200104)44:4<912::AID-ANR148>3.0.CO;2-5. Arthritis Rheum. 2001. PMID: 11318006 Free article.

8

Response of Wegener's granulomatosis to anti-CD20 chimeric monoclonal antibody therapy.

Specks U, Fervenza FC, McDonald TJ, Hogan MC. Specks U, et al. Arthritis Rheum. 2001 Dec;44(12):2836-40. doi: 10.1002/1529-0131(200112)44:12<2836::aid-art471>3.0.co;2-w. Arthritis Rheum. 2001. PMID: 11762944 Free article.

9

Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA.

Capizzi SA, Viss MA, Hummel AM, Fass DN, Specks U. Capizzi SA, et al. Among authors: specks u. Kidney Int. 2003 Feb;63(2):756-60. doi: 10.1046/j.1523-1755.2003.00765.x. Kidney Int. 2003. PMID: 12631144 Free article.

10

Wegener's granulomatosis presenting as multiple bilateral renal masses.

Leung N, Ytterberg SR, Blute ML, Lager DJ, Specks U, Fervenza FC. Leung N, et al. Among authors: specks u. Nephrol Dial Transplant. 2004 Apr;19(4):984-7. doi: 10.1093/ndt/gfh058. Nephrol Dial Transplant. 2004. PMID: 15031361 No abstract available.

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