Chen L - Search Results

1

Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D₂/D₃ Receptor Bitopic Ligands.

Shaik AB, Boateng CA, Battiti FO, Bonifazi A, Cao J, Chen L, Chitsazi R, Ravi S, Lee KH, Shi L, Newman AH. Shaik AB, et al. Among authors: chen l. J Med Chem. 2021 Oct 28;64(20):15313-15333. doi: 10.1021/acs.jmedchem.1c01353. Epub 2021 Oct 12. J Med Chem. 2021. PMID: 34636551 Free PMC article.

2

Efficient synthesis and identification of novel propane-1,3-diamino bridged CCR5 antagonists with variation on the basic center carrier.

Fan X, Zhang HS, Chen L, Long YQ. Fan X, et al. Among authors: chen l. Eur J Med Chem. 2010 Jul;45(7):2827-40. doi: 10.1016/j.ejmech.2010.03.003. Epub 2010 Mar 7. Eur J Med Chem. 2010. PMID: 20347189

3

Forward- and reverse-synthesis of piperazinopiperidine amide analogs: a general access to structurally diverse 4-piperazinopiperidine-based CCR5 antagonists.

Feng DZ, Song YL, Jiang XH, Chen L, Long YQ. Feng DZ, et al. Among authors: chen l. Org Biomol Chem. 2007 Aug 21;5(16):2690-7. doi: 10.1039/b707175b. Org Biomol Chem. 2007. PMID: 18019544

4

Discovery of Norisoboldine Analogue III₁₁ as a Novel and Potent Aryl Hydrocarbon Receptor Agonist for the Treatment of Ulcerative Colitis.

Lin L, Liu Y, Chen L, Dai Y, Xia Y. Lin L, et al. Among authors: chen l. J Med Chem. 2023 May 25;66(10):6869-6888. doi: 10.1021/acs.jmedchem.3c00287. Epub 2023 May 8. J Med Chem. 2023. PMID: 37154394

5

Development and therapeutic perspectives of CXCR4 antagonists for disease therapy.

Yang J, Tian E, Chen L, Liu Z, Ren Y, Mao W, Zhang Y, Zhang J. Yang J, et al. Among authors: chen l. Eur J Med Chem. 2024 Sep 5;275:116594. doi: 10.1016/j.ejmech.2024.116594. Epub 2024 Jun 11. Eur J Med Chem. 2024. PMID: 38879970 Review.

6

A novel cyanine photosensitizer for sequential dual-site GSH depletion and ROS-potentiated cancer photodynamic therapy.

Chen L, Yang J, Su F, Liu Z, Huang S, Zhang J, Li J, Mao W. Chen L, et al. Eur J Med Chem. 2024 Dec 12;283:117165. doi: 10.1016/j.ejmech.2024.117165. Online ahead of print. Eur J Med Chem. 2024. PMID: 39689415

7

Discovery of novel (S)-alpha-phenyl-gamma-amino butanamide containing CCR5 antagonists via functionality inversion approach.

Zhang HS, Feng DZ, Chen L, Long YQ. Zhang HS, et al. Among authors: chen l. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2219-23. doi: 10.1016/j.bmcl.2010.02.023. Epub 2010 Feb 10. Bioorg Med Chem Lett. 2010. PMID: 20207141

8

Comprehensive Insights that Targeting PIM for Cancer Therapy: Prospects and Obstacles.

Chen L, Mao W, Ren C, Li J, Zhang J. Chen L, et al. J Med Chem. 2024 Jan 11;67(1):38-64. doi: 10.1021/acs.jmedchem.3c01802. Epub 2024 Jan 2. J Med Chem. 2024. PMID: 38164076 Review.

9

Recent discovery and development of AXL inhibitors as antitumor agents.

Liu Z, Chen L, Zhang J, Yang J, Xiao X, Shan L, Mao W. Liu Z, et al. Among authors: chen l. Eur J Med Chem. 2024 Jun 5;272:116475. doi: 10.1016/j.ejmech.2024.116475. Epub 2024 May 3. Eur J Med Chem. 2024. PMID: 38714043 Review.

10

Design, Synthesis, and Antitumor Efficacy of Substituted 2-Amino[1,2,4]triazolopyrimidines and Related Heterocycles as Dual Inhibitors for Microtubule Polymerization and Janus Kinase 2.

Chen L, Hu Y, Lu Z, Lin Z, Li L, Wu JQ, Yu ZL, Wang C, Chen WH, Hu J. Chen L, et al. Among authors: chen wh. J Med Chem. 2023 Nov 9;66(21):15006-15024. doi: 10.1021/acs.jmedchem.3c01690. Epub 2023 Oct 19. J Med Chem. 2023. PMID: 37856840

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