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Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-11C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and σ1-Receptor-Targeted PET Imaging.
Haider A, Herde AM, Krämer SD, Varisco J, Keller C, Frauenknecht K, Auberson YP, Temme L, Robaa D, Sippl W, Schibli R, Wünsch B, Mu L, Ametamey SM. Haider A, et al. J Nucl Med. 2019 Aug;60(8):1167-1173. doi: 10.2967/jnumed.118.221051. Epub 2019 Jan 25. J Nucl Med. 2019. PMID: 30683765 Free PMC article.
Structure-Affinity Relationships of 2,3,4,5-Tetrahydro-1H-3-benzazepine and 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-7-amine Analogues and the Discovery of a Radiofluorinated 2,3,4,5-Tetrahydro-1H-3-benzazepine Congener for Imaging GluN2B Subunit-Containing N-Methyl-d-aspartate Receptors.
Ahmed H, Haider A, Varisco J, Stanković M, Wallimann R, Gruber S, Iten I, Häne S, Müller Herde A, Keller C, Schibli R, Schepmann D, Mu L, Wünsch B, Ametamey SM. Ahmed H, et al. Among authors: haider a. J Med Chem. 2019 Nov 14;62(21):9450-9470. doi: 10.1021/acs.jmedchem.9b00812. Epub 2019 Oct 28. J Med Chem. 2019. PMID: 31657559
1,418 results