Liu DR - Search Results

1

Disulfide-compatible phage-assisted continuous evolution in the periplasmic space.

Morrison MS, Wang T, Raguram A, Hemez C, Liu DR. Morrison MS, et al. Among authors: liu dr. Nat Commun. 2021 Oct 13;12(1):5959. doi: 10.1038/s41467-021-26279-8. Nat Commun. 2021. PMID: 34645844 Free PMC article.

2

Dissecting protein structure and function using directed evolution.

Yuen CM, Liu DR. Yuen CM, et al. Among authors: liu dr. Nat Methods. 2007 Dec;4(12):995-7. doi: 10.1038/nmeth1207-995. Nat Methods. 2007. PMID: 18049466 Free PMC article. Review.

3

A system for the continuous directed evolution of biomolecules.

Esvelt KM, Carlson JC, Liu DR. Esvelt KM, et al. Among authors: liu dr. Nature. 2011 Apr 28;472(7344):499-503. doi: 10.1038/nature09929. Epub 2011 Apr 10. Nature. 2011. PMID: 21478873 Free PMC article.

4

Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution.

Dickinson BC, Leconte AM, Allen B, Esvelt KM, Liu DR. Dickinson BC, et al. Among authors: liu dr. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9007-12. doi: 10.1073/pnas.1220670110. Epub 2013 May 14. Proc Natl Acad Sci U S A. 2013. PMID: 23674678 Free PMC article.

5

Negative selection and stringency modulation in phage-assisted continuous evolution.

Carlson JC, Badran AH, Guggiana-Nilo DA, Liu DR. Carlson JC, et al. Among authors: liu dr. Nat Chem Biol. 2014 Mar;10(3):216-22. doi: 10.1038/nchembio.1453. Epub 2014 Feb 2. Nat Chem Biol. 2014. PMID: 24487694 Free PMC article.

6

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity.

Guilinger JP, Pattanayak V, Reyon D, Tsai SQ, Sander JD, Joung JK, Liu DR. Guilinger JP, et al. Among authors: liu dr. Nat Methods. 2014 Apr;11(4):429-35. doi: 10.1038/nmeth.2845. Epub 2014 Feb 16. Nat Methods. 2014. PMID: 24531420 Free PMC article.

7

A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.

Dickinson BC, Packer MS, Badran AH, Liu DR. Dickinson BC, et al. Among authors: liu dr. Nat Commun. 2014 Oct 30;5:5352. doi: 10.1038/ncomms6352. Nat Commun. 2014. PMID: 25355134 Free PMC article.

8

In vivo continuous directed evolution.

Badran AH, Liu DR. Badran AH, et al. Among authors: liu dr. Curr Opin Chem Biol. 2015 Feb;24:1-10. doi: 10.1016/j.cbpa.2014.09.040. Epub 2014 Nov 7. Curr Opin Chem Biol. 2015. PMID: 25461718 Free PMC article. Review.

9

Methods for the directed evolution of proteins.

Packer MS, Liu DR. Packer MS, et al. Among authors: liu dr. Nat Rev Genet. 2015 Jul;16(7):379-94. doi: 10.1038/nrg3927. Epub 2015 Jun 9. Nat Rev Genet. 2015. PMID: 26055155 Review.

10

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.

Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR. Hubbard BP, et al. Among authors: liu dr. Nat Methods. 2015 Oct;12(10):939-42. doi: 10.1038/nmeth.3515. Epub 2015 Aug 10. Nat Methods. 2015. PMID: 26258293 Free PMC article.

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