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STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells.
Richart L, Lapi E, Pancaldi V, Cuenca-Ardura M, Pau EC, Madrid-Mencía M, Neyret-Kahn H, Radvanyi F, Rodríguez JA, Cuartero Y, Serra F, Le Dily F, Valencia A, Marti-Renom MA, Real FX. Richart L, et al. Nucleic Acids Res. 2021 Nov 8;49(19):11005-11021. doi: 10.1093/nar/gkab864. Nucleic Acids Res. 2021. PMID: 34648034 Free PMC article.
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.
Balbás-Martínez C, Sagrera A, Carrillo-de-Santa-Pau E, Earl J, Márquez M, Vazquez M, Lapi E, Castro-Giner F, Beltran S, Bayés M, Carrato A, Cigudosa JC, Domínguez O, Gut M, Herranz J, Juanpere N, Kogevinas M, Langa X, López-Knowles E, Lorente JA, Lloreta J, Pisano DG, Richart L, Rico D, Salgado RN, Tardón A, Chanock S, Heath S, Valencia A, Losada A, Gut I, Malats N, Real FX. Balbás-Martínez C, et al. Among authors: richart l. Nat Genet. 2013 Dec;45(12):1464-9. doi: 10.1038/ng.2799. Epub 2013 Oct 13. Nat Genet. 2013. PMID: 24121791 Free PMC article.
c-MYC partners with BPTF in human cancer.
Richart L, Real FX, Sanchez-Arevalo Lobo VJ. Richart L, et al. Mol Cell Oncol. 2016 Feb 18;3(3):e1152346. doi: 10.1080/23723556.2016.1152346. eCollection 2016 May. Mol Cell Oncol. 2016. PMID: 27314097 Free PMC article.
Bptf determines oncogenic addiction in aggressive B-cell lymphomas.
Richart L, Felipe I, Delgado P, Andrés MP, Prieto J, Pozo ND, García JF, Piris MA, Ramiro A, Real FX. Richart L, et al. Oncogene. 2020 Jun;39(25):4884-4895. doi: 10.1038/s41388-020-1331-3. Epub 2020 May 25. Oncogene. 2020. PMID: 32451433
XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation.
Richart L, Picod-Chedotel ML, Wassef M, Macario M, Aflaki S, Salvador MA, Héry T, Dauphin A, Wicinski J, Chevrier V, Pastor S, Guittard G, Le Cam S, Kamhawi H, Castellano R, Guasch G, Charafe-Jauffret E, Heard E, Margueron R, Ginestier C. Richart L, et al. Cell. 2022 Jun 9;185(12):2164-2183.e25. doi: 10.1016/j.cell.2022.04.034. Epub 2022 May 20. Cell. 2022. PMID: 35597241 Free article.
Drugging histone methyltransferases in cancer.
Richart L, Margueron R. Richart L, et al. Curr Opin Chem Biol. 2020 Jun;56:51-62. doi: 10.1016/j.cbpa.2019.11.009. Epub 2020 Jan 23. Curr Opin Chem Biol. 2020. PMID: 31981999 Review.
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