Brouwer AJ - Search Results

1

Hydrolytic (In)stability of Methacrylate Esters in Covalently Cross-Linked Hydrogels Based on Chondroitin Sulfate and Hyaluronic Acid Methacrylate.

Schuurmans CCL, Brouwer AJ, Jong JAW, Boons GPH, Hennink WE, Vermonden T. Schuurmans CCL, et al. Among authors: brouwer aj. ACS Omega. 2021 Sep 28;6(40):26302-26310. doi: 10.1021/acsomega.1c03395. eCollection 2021 Oct 12. ACS Omega. 2021. PMID: 34660989 Free PMC article.

2

Synthesis of monophosphoryl lipid A using 2-naphtylmethyl ethers as permanent protecting groups.

Verpalen ECJM, Brouwer AJ, Boons GJ. Verpalen ECJM, et al. Among authors: brouwer aj. Carbohydr Res. 2020 Dec;498:108152. doi: 10.1016/j.carres.2020.108152. Epub 2020 Sep 25. Carbohydr Res. 2020. PMID: 33032087 Free article.

3

Potential peptidic proteasome inhibitors by incorporation of an electrophilic trap based on amino acid derived α-substituted sulfonyl fluorides.

Herrero Alvarez N, van de Langemheen H, Brouwer AJ, Liskamp RMJ. Herrero Alvarez N, et al. Among authors: brouwer aj. Bioorg Med Chem. 2017 Oct 1;25(19):5055-5063. doi: 10.1016/j.bmc.2017.07.019. Epub 2017 Jul 12. Bioorg Med Chem. 2017. PMID: 28734665 Free article.

4

Synthesis and biological evaluation of novel irreversible serine protease inhibitors using amino acid based sulfonyl fluorides as an electrophilic trap.

Brouwer AJ, Ceylan T, Jonker AM, van der Linden T, Liskamp RM. Brouwer AJ, et al. Bioorg Med Chem. 2011 Apr 1;19(7):2397-406. doi: 10.1016/j.bmc.2011.02.014. Epub 2011 Feb 13. Bioorg Med Chem. 2011. PMID: 21421320

5

Potent and Highly Selective Inhibitors of the Proteasome Trypsin-like Site by Incorporation of Basic Side Chain Containing Amino Acid Derived Sulfonyl Fluorides.

Artschwager R, Ward DJ, Gannon S, Brouwer AJ, van de Langemheen H, Kowalski H, Liskamp RMJ. Artschwager R, et al. Among authors: brouwer aj. J Med Chem. 2018 Jun 28;61(12):5395-5411. doi: 10.1021/acs.jmedchem.8b00685. Epub 2018 Jun 13. J Med Chem. 2018. PMID: 29782167 Free article.

6

Scaffold optimization in discontinuous epitope containing protein mimics of gp120 using smart libraries.

Mulder GE, Quarles van Ufford HL, van Ameijde J, Brouwer AJ, Kruijtzer JA, Liskamp RM. Mulder GE, et al. Among authors: brouwer aj. Org Biomol Chem. 2013 Apr 28;11(16):2676-84. doi: 10.1039/c3ob27470e. Org Biomol Chem. 2013. PMID: 23467699

7

Synthesis of cyclic peptides containing a thioester handle for native chemical ligation.

van de Langemheen H, Brouwer AJ, Kemmink J, Kruijtzer JA, Liskamp RM. van de Langemheen H, et al. Among authors: brouwer aj. J Org Chem. 2012 Nov 16;77(22):10058-64. doi: 10.1021/jo3015566. Epub 2012 Nov 5. J Org Chem. 2012. PMID: 23078179

8

Synthesis of the TACO scaffold as a new selectively deprotectable conformationally restricted triazacyclophane based scaffold.

Brouwer AJ, van de Langemheen H, Ciaffoni A, Schilder KE, Liskamp RM. Brouwer AJ, et al. Org Lett. 2014 Jun 6;16(11):3106-9. doi: 10.1021/ol5012218. Epub 2014 May 23. Org Lett. 2014. PMID: 24856258

9

Peptide microarray analysis of the cross-talk between O-GlcNAcylation and tyrosine phosphorylation.

Shi J, Tomašič T, Sharif S, Brouwer AJ, Anderluh M, Ruijtenbeek R, Pieters RJ. Shi J, et al. Among authors: brouwer aj. FEBS Lett. 2017 Jul;591(13):1872-1883. doi: 10.1002/1873-3468.12708. Epub 2017 Jun 27. FEBS Lett. 2017. PMID: 28580691 Free article.

10

Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.

Brouwer AJ, Bunschoten A, Liskamp RM. Brouwer AJ, et al. Bioorg Med Chem. 2007 Nov 15;15(22):6985-93. doi: 10.1016/j.bmc.2007.07.045. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17869119

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