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DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia.
Lam LKM, Murphy S, Kokkinaki D, Venosa A, Sherrill-Mix S, Casu C, Rivella S, Weiner A, Park J, Shin S, Vaughan AE, Hahn BH, Odom John AR, Meyer NJ, Hunter CA, Worthen GS, Mangalmurti NS. Lam LKM, et al. Among authors: hahn bh. Sci Transl Med. 2021 Oct 20;13(616):eabj1008. doi: 10.1126/scitranslmed.abj1008. Epub 2021 Oct 20. Sci Transl Med. 2021. PMID: 34669439 Free PMC article.
SARS-CoV-2 mRNA vaccination exposes progressive adaptive immune dysfunction in patients with chronic lymphocytic leukemia.
Qin K, Honjo K, Sherrill-Mix S, Liu W, Stoltz R, Oman AK, Hall LA, Li R, Sterrett S, Frederick ER, Lancaster JR, Narkhede M, Mehta A, Ogunsile FJ, Patel RB, Ketas TJ, Cruz Portillo VM, Cupo A, Larimer BM, Bansal A, Goepfert PA, Hahn BH, Davis RS. Qin K, et al. Among authors: hahn bh. medRxiv [Preprint]. 2022 Dec 20:2022.12.19.22283645. doi: 10.1101/2022.12.19.22283645. medRxiv. 2022. Update in: PLoS Med. 2023 Jun 29;20(6):e1004157. doi: 10.1371/journal.pmed.1004157 PMID: 36597532 Free PMC article. Updated. Preprint.
Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study.
Qin K, Honjo K, Sherrill-Mix S, Liu W, Stoltz RM, Oman AK, Hall LA, Li R, Sterrett S, Frederick ER, Lancaster JR, Narkhede M, Mehta A, Ogunsile FJ, Patel RB, Ketas TJ, Cruz Portillo VM, Cupo A, Larimer BM, Bansal A, Goepfert PA, Hahn BH, Davis RS. Qin K, et al. Among authors: hahn bh. PLoS Med. 2023 Jun 29;20(6):e1004157. doi: 10.1371/journal.pmed.1004157. eCollection 2023 Jun. PLoS Med. 2023. PMID: 37384638 Free PMC article.
The Origin of COVID-19 and Why It Matters.
Morens DM, Breman JG, Calisher CH, Doherty PC, Hahn BH, Keusch GT, Kramer LD, LeDuc JW, Monath TP, Taubenberger JK. Morens DM, et al. Among authors: hahn bh. Am J Trop Med Hyg. 2020 Sep;103(3):955-959. doi: 10.4269/ajtmh.20-0849. Am J Trop Med Hyg. 2020. PMID: 32700664 Free PMC article.
CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies.
Richard J, Sannier G, Zhu L, Prévost J, Marchitto L, Benlarbi M, Beaudoin-Bussières G, Kim H, Sun Y, Chatterjee D, Medjahed H, Bourassa C, Delgado G-G, Dubé M, Kirchhoff F, Hahn BH, Kumar P, Kaufmann DE, Finzi A. Richard J, et al. Among authors: hahn bh. mBio. 2024 Nov 13;15(11):e0182724. doi: 10.1128/mbio.01827-24. Epub 2024 Oct 7. mBio. 2024. PMID: 39373535 Free PMC article.
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity.
Marchitto L, Richard J, Prévost J, Tauzin A, Yang D, Chiu T-J, Chen H-C, Díaz-Salinas MA, Nayrac M, Benlarbi M, Beaudoin-Bussières G, Anand SP, Dionne K, Bélanger É, Chatterjee D, Medjahed H, Bourassa C, Tolbert WD, Hahn BH, Munro JB, Pazgier M, Smith AB 3rd, Finzi A. Marchitto L, et al. Among authors: hahn bh. J Virol. 2024 Oct 22;98(10):e0101624. doi: 10.1128/jvi.01016-24. Epub 2024 Sep 9. J Virol. 2024. PMID: 39248460
632 results