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Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.
Pablos I, Machado Y, de Jesus HCR, Mohamud Y, Kappelhoff R, Lindskog C, Vlok M, Bell PA, Butler GS, Grin PM, Cao QT, Nguyen JP, Solis N, Abbina S, Rut W, Vederas JC, Szekely L, Szakos A, Drag M, Kizhakkedathu JN, Mossman K, Hirota JA, Jan E, Luo H, Banerjee A, Overall CM. Pablos I, et al. Among authors: machado y. Cell Rep. 2021 Oct 26;37(4):109892. doi: 10.1016/j.celrep.2021.109892. Epub 2021 Oct 9. Cell Rep. 2021. PMID: 34672947 Free PMC article.
Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.
Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, Franzke CW, Overall CM, Granville DJ. Russo V, et al. Among authors: machado y. Sci Rep. 2018 Jun 26;8(1):9690. doi: 10.1038/s41598-018-28070-0. Sci Rep. 2018. PMID: 29946113 Free PMC article.
Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CLpro main protease (Mpro) from proteomic identification of P6-P6' active site specificity.
Cesar Ramos de Jesus H, Solis N, Machado Y, Pablos I, Bell PA, Kappelhoff R, Grin PM, Sorgi CA, Butler GS, Overall CM. Cesar Ramos de Jesus H, et al. Among authors: machado y. J Virol. 2024 Jun 13;98(6):e0004924. doi: 10.1128/jvi.00049-24. Epub 2024 May 14. J Virol. 2024. PMID: 38742901 Free PMC article.
Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy.
Machado Y, Duinkerken S, Hoepflinger V, Mayr M, Korotchenko E, Kurtaj A, Pablos I, Steiner M, Stoecklinger A, Lübbers J, Schmid M, Ritter U, Scheiblhofer S, Ablinger M, Wally V, Hochmann S, Raninger AM, Strunk D, van Kooyk Y, Thalhamer J, Weiss R. Machado Y, et al. J Control Release. 2017 Nov 28;266:87-99. doi: 10.1016/j.jconrel.2017.09.020. Epub 2017 Sep 14. J Control Release. 2017. PMID: 28919557
Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.
Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R. Machado Y, et al. J Allergy Clin Immunol. 2016 May;137(5):1525-34. doi: 10.1016/j.jaci.2015.09.026. Epub 2015 Nov 11. J Allergy Clin Immunol. 2016. PMID: 26559323 Free PMC article.
59 results