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The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation.
Sparber F, De Gregorio C, Steckholzer S, Ferreira FM, Dolowschiak T, Ruchti F, Kirchner FR, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S. Sparber F, et al. Among authors: ruchti f. Cell Host Microbe. 2019 Mar 13;25(3):389-403.e6. doi: 10.1016/j.chom.2019.02.002. Cell Host Microbe. 2019. PMID: 30870621 Free article.
Host Immunity to Malassezia in Health and Disease.
Sparber F, Ruchti F, LeibundGut-Landmann S. Sparber F, et al. Among authors: ruchti f. Front Cell Infect Microbiol. 2020 May 5;10:198. doi: 10.3389/fcimb.2020.00198. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32477963 Free PMC article. Review.
The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation.
Goh JPZ, Ruchti F, Poh SE, Koh WLC, Tan KY, Lim YT, Thng STG, Sobota RM, Hoon SS, Liu C, O'Donoghue AJ, LeibundGut-Landmann S, Oon HH, Li H, Dawson TL Jr. Goh JPZ, et al. Among authors: ruchti f. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2212533119. doi: 10.1073/pnas.2212533119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442106 Free PMC article.
Card9 and MyD88 differentially regulate Th17 immunity to the commensal yeast Malassezia in the murine skin.
Tuor M, Stappers MHT, Ruchti F, Desgardin A, Sparber F, Orr SJ, Gow NAR, LeibundGut-Landmann S. Tuor M, et al. Among authors: ruchti f. bioRxiv [Preprint]. 2024 Jul 16:2024.07.12.603211. doi: 10.1101/2024.07.12.603211. bioRxiv. 2024. Update in: Mucosal Immunol. 2024 Nov 22:S1933-0219(24)00112-0. doi: 10.1016/j.mucimm.2024.11.004 PMID: 39071334 Free PMC article. Updated. Preprint.
20 results