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NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions.
Cazzetta V, Bruni E, Terzoli S, Carenza C, Franzese S, Piazza R, Marzano P, Donadon M, Torzilli G, Cimino M, Simonelli M, Bello L, Villa A, Tan L, Ravens S, Prinz I, Supino D, Colombo FS, Lugli E, Marcenaro E, Vivier E, Della Bella S, Mikulak J, Mavilio D. Cazzetta V, et al. Among authors: bruni e. Cell Rep. 2021 Oct 19;37(3):109871. doi: 10.1016/j.celrep.2021.109871. Cell Rep. 2021. PMID: 34686325 Free article.
Intrahepatic CD69+Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression.
Bruni E, Cimino MM, Donadon M, Carriero R, Terzoli S, Piazza R, Ravens S, Prinz I, Cazzetta V, Marzano P, Kunderfranco P, Peano C, Soldani C, Franceschini B, Colombo FS, Garlanda C, Mantovani A, Torzilli G, Mikulak J, Mavilio D. Bruni E, et al. J Immunother Cancer. 2022 Jul;10(7):e004579. doi: 10.1136/jitc-2022-004579. J Immunother Cancer. 2022. PMID: 35863820 Free PMC article.
NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer.
Mikulak J, Oriolo F, Bruni E, Roberto A, Colombo FS, Villa A, Bosticardo M, Bortolomai I, Lo Presti E, Meraviglia S, Dieli F, Vetrano S, Danese S, Della Bella S, Carvello MM, Sacchi M, Cugini G, Colombo G, Klinger M, Spaggiari P, Roncalli M, Prinz I, Ravens S, di Lorenzo B, Marcenaro E, Silva-Santos B, Spinelli A, Mavilio D. Mikulak J, et al. Among authors: bruni e. JCI Insight. 2019 Dec 19;4(24):e125884. doi: 10.1172/jci.insight.125884. JCI Insight. 2019. PMID: 31689241 Free PMC article.
A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood.
Tan L, Fichtner AS, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs CF, Ravens S, Prinz I. Tan L, et al. Among authors: bruni e. Sci Immunol. 2021 Apr 23;6(58):eabf0125. doi: 10.1126/sciimmunol.abf0125. Sci Immunol. 2021. PMID: 33893173
CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML.
Salomé B, Gomez-Cadena A, Loyon R, Suffiotti M, Salvestrini V, Wyss T, Vanoni G, Ruan DF, Rossi M, Tozzo A, Tentorio P, Bruni E, Riether C, Jacobsen EM, Jandus P, Conrad C, Hoenig M, Schulz A, Michaud K, Della Porta MG, Salvatore S, Ho PC, Gfeller D, Ochsenbein A, Mavilio D, Curti A, Marcenaro E, Steinle A, Horowitz A, Romero P, Trabanelli S, Jandus C. Salomé B, et al. Among authors: bruni e. Blood Adv. 2019 Nov 26;3(22):3674-3687. doi: 10.1182/bloodadvances.2018030478. Blood Adv. 2019. PMID: 31765481 Free PMC article.
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.
Trabanelli S, Chevalier MF, Martinez-Usatorre A, Gomez-Cadena A, Salomé B, Lecciso M, Salvestrini V, Verdeil G, Racle J, Papayannidis C, Morita H, Pizzitola I, Grandclément C, Bohner P, Bruni E, Girotra M, Pallavi R, Falvo P, Leibundgut EO, Baerlocher GM, Carlo-Stella C, Taurino D, Santoro A, Spinelli O, Rambaldi A, Giarin E, Basso G, Tresoldi C, Ciceri F, Gfeller D, Akdis CA, Mazzarella L, Minucci S, Pelicci PG, Marcenaro E, McKenzie ANJ, Vanhecke D, Coukos G, Mavilio D, Curti A, Derré L, Jandus C. Trabanelli S, et al. Among authors: bruni e. Nat Commun. 2017 Sep 19;8(1):593. doi: 10.1038/s41467-017-00678-2. Nat Commun. 2017. PMID: 28928446 Free PMC article.
93 results