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Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9.
Li HL, Fujimoto N, Sasakawa N, Shirai S, Ohkame T, Sakuma T, Tanaka M, Amano N, Watanabe A, Sakurai H, Yamamoto T, Yamanaka S, Hotta A. Li HL, et al. Among authors: hotta a. Stem Cell Reports. 2015 Jan 13;4(1):143-154. doi: 10.1016/j.stemcr.2014.10.013. Epub 2014 Nov 26. Stem Cell Reports. 2015. PMID: 25434822 Free PMC article.
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H. Imamura K, et al. Among authors: hotta a. Sci Transl Med. 2017 May 24;9(391):eaaf3962. doi: 10.1126/scitranslmed.aaf3962. Sci Transl Med. 2017. PMID: 28539470 Free article.
295 results