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Page 1
Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform.
Tsan YC, DePalma SJ, Zhao YT, Capilnasiu A, Wu YW, Elder B, Panse I, Ufford K, Matera DL, Friedline S, O'Leary TS, Wubshet N, Ho KKY, Previs MJ, Nordsletten D, Isom LL, Baker BM, Liu AP, Helms AS. Tsan YC, et al. Among authors: helms as. Nat Commun. 2021 Oct 25;12(1):6167. doi: 10.1038/s41467-021-26496-1. Nat Commun. 2021. PMID: 34697315 Free PMC article.
Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry.
Abou Alaiwi S, Roston TM, Marstrand P, Claggett BL, Parikh VN, Helms AS, Ingles J, Lampert R, Lakdawala NK, Michels M, Owens AT, Rossano JW, Saberi S, Abrams DJ, Ashley EA, Semsarian C, Stendahl JC, Ware JS, Miller E, Ryan TD, Russell MW, Day SM, Olivotto I, Vissing CR, Ho CY. Abou Alaiwi S, et al. Among authors: helms as. Circulation. 2023 Aug;148(5):394-404. doi: 10.1161/CIRCULATIONAHA.122.062517. Epub 2023 May 25. Circulation. 2023. PMID: 37226762 Free PMC article.
Matrix Architecture and Mechanics Regulate Myofibril Organization, Costamere Assembly, and Contractility in Engineered Myocardial Microtissues.
DePalma SJ, Jilberto J, Stis AE, Huang DD, Lo J, Davidson CD, Chowdhury A, Kent RN 3rd, Jewett ME, Kobeissi H, Chen CS, Lejeune E, Helms AS, Nordsletten DA, Baker BM. DePalma SJ, et al. Among authors: helms as. Adv Sci (Weinh). 2024 Dec;11(47):e2309740. doi: 10.1002/advs.202309740. Epub 2024 Nov 18. Adv Sci (Weinh). 2024. PMID: 39558513 Free PMC article.
Low Penetrance Sarcomere Variants Contribute to Additive Risk in Hypertrophic Cardiomyopathy.
Meisner JK, Renberg A, Smith ED, Tsan YC, Elder B, Bullard A, Merritt O, Zheng SL, Lakdawala N, Owens A, Ryan TD, Miller EM, Rossano J, Lin KY, Claggett B, Ashley E, Michels M, Lampert R, Stendahl JC, Abrahams D, Semsarian C, Parikh VN, Wheeler M, Ingles J, Day SM, Saberi S, Russell MW, Previs M, Ho C, Ware JS, Helms AS. Meisner JK, et al. Among authors: helms as. Circulation. 2024 Dec 5. doi: 10.1161/CIRCULATIONAHA.124.069398. Online ahead of print. Circulation. 2024. PMID: 39633578
Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes.
Monteiro da Rocha A, Guerrero-Serna G, Helms A, Luzod C, Mironov S, Russell M, Jalife J, Day SM, Smith GD, Herron TJ. Monteiro da Rocha A, et al. J Mol Cell Cardiol. 2016 Oct;99:197-206. doi: 10.1016/j.yjmcc.2016.09.004. Epub 2016 Sep 10. J Mol Cell Cardiol. 2016. PMID: 27620334 Free PMC article.
HSC70 is a chaperone for wild-type and mutant cardiac myosin binding protein C.
Glazier AA, Hafeez N, Mellacheruvu D, Basrur V, Nesvizhskii AI, Lee LM, Shao H, Tang V, Yob JM, Gestwicki JE, Helms AS, Day SM. Glazier AA, et al. Among authors: helms as. JCI Insight. 2018 Jun 7;3(11):e99319. doi: 10.1172/jci.insight.99319. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875314 Free PMC article.
67 results