Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Kinnebrew M, Woolley RE, Ansell TB, Byrne EFX, Frigui S, Luchetti G, Sircar R, Nachtergaele S, Mydock-McGrane L, Krishnan K, Newstead S, Sansom MSP, Covey DF, Siebold C, Rohatgi R.
Kinnebrew M, et al. Among authors: frigui s.
Sci Adv. 2022 Jun 3;8(22):eabm5563. doi: 10.1126/sciadv.abm5563. Epub 2022 Jun 3.
Sci Adv. 2022.
PMID: 35658032
Free PMC article.